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- Title
Mirtazapine for Refractory Gastroparesis.
- Authors
Marella, Hemnishil K.; Saleem, Nasir; Olden, Kevin
- Abstract
Gastroparesis is a chronic condition of delayed gastric emptying in the absence of mechanical outlet obstruction. We report a 47-year-old African American woman with diabetic gastroparesis who presented with intractable nausea, vomiting, and decreased oral intake with electrolyte disturbances. The patient's symptoms were difficult to control with antiemetic and conventional prokinetic agents, and she was started on mirtazapine 15 mg nightly. She experienced an almost complete symptom relief and was able to tolerate solid food within 24-48 hours. We highlight the role of mirtazapine, a 5-HT1a agonist, as an effective therapy for refractory gastroparesis.
- Subjects
CHRONIC diseases; DIABETES; NAUSEA; VOMITING; MIRTAZAPINE; GASTROPARESIS
- Publication
ACG Case Reports Journal, 2019, Vol 6, Issue 10, p1
- ISSN
2326-3253
- Publication type
Article
- DOI
10.14309/crj.0000000000000256