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- Title
The Impact of Timing of Exercise Initiation on Weight Loss: An 18-Month Randomized Clinical Trial.
- Authors
Catenacci, Victoria A.; Ostendorf, Danielle M.; Pan, Zhaoxing; Bing, Kristen; Wayland, Liza T.; Seyoum, Emmanuel; Stauffer, Brian L.; Phelan, Suzanne; Creasy, Seth A.; Caldwell, Ann E.; Wyatt, Holly R.; Bessesen, Daniel H.; Melanson, Edward L.
- Abstract
<bold>Objective: </bold>This study aimed to evaluate the impact of timing of exercise initiation on weight loss within a behavioral weight loss program.<bold>Methods: </bold>Adults with overweight or obesity (N = 170; age 18-55 years; BMI 25-42 kg/m2 ; 83.5% women) were enrolled in an 18-month behavioral weight loss program consisting of a reduced-calorie diet, exercise, and group-based support. The standard group (STD) received a supervised exercise program (progressing to 300 min/wk of moderate-intensity aerobic exercise) during months 0 to 6. The sequential group (SEQ) was asked to refrain from changing exercise during months 0 to 6 and received the supervised exercise program during months 7 to 12. On completion of supervised exercise, both groups were instructed to continue 300 min/wk of moderate-intensity exercise for the study duration.<bold>Results: </bold>At 6 months, the STD group exhibited greater reductions in body weight (-8.7 ± 0.7 kg) compared with the SEQ group (-6.9 ± 0.6 kg; P = 0.047). Between 6 and 18 months, the STD group regained more weight (2.5 ± 0.8 kg vs. 0.0 ± 0.8 kg; P = 0.02). At 18 months, there were no between-group differences in changes in weight (STD: -6.9 ± 1.2 kg; SEQ: -7.9 ± 1.2 kg), fat mass, lean mass, physical activity, or attrition.<bold>Conclusions: </bold>Both immediate and delayed exercise initiation within a behavioral weight loss program resulted in clinically meaningful weight loss at 18 months. Thus, timing of exercise initiation can be personalized based on patient preference.
- Subjects
WEIGHT loss; AEROBIC exercises; EXERCISE; CLINICAL trials; LEAN body mass; LOW-fat diet; AQUATIC exercises; OBESITY treatment; OBESITY; BODY composition; BLOOD pressure; BODY weight; TIME; BEHAVIOR therapy; MEDICAL care; PATIENTS; RANDOMIZED controlled trials; COMBINED modality therapy; STATISTICAL sampling; HEALTH promotion
- Publication
Obesity (19307381), 2019, Vol 27, Issue 11, p1828
- ISSN
1930-7381
- Publication type
journal article
- DOI
10.1002/oby.22624