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- Title
Hemmbarkeit ptoteolytischer Enzyme in pathologischen Nasensekreten und von Leukocytenproteasen durch den natürlichen Proteaseninhibitor des Nasensekrets.
- Authors
HOCHSTRASSER, K.; REICHERT, R.; MATZNER, MONIKA; WERLE, E.
- Abstract
Under physiological conditions human nasal mucus contains a proteinase inhibitor which inhibits trypsin, chymotrypsin, pronase, and leucocytic proteases. The inhibitor is not identical with inhibitors from blood serum. In pathological conditions proteolytic activity appears in human nasal mucus. This activity, like that of leucocytic proteases, is blocked by the inhibitor from normal nasal mucus. We propose that the inhibitor protects the nasal mucus membrane against proteases from decomposed leucocytes. The decrease of the inhibitor level in nasal mucus in different rhinopathia may be explained as an interaction of inhibitor and leucocytic proteases or other unidentified proteases.
- Publication
Clinical Chemistry & Laboratory Medicine, 1972, Vol 10, Issue 3, p104
- ISSN
1434-6621
- Publication type
Article