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- Title
Vitamin D deficiency in women with polycystic ovary syndrome.
- Authors
Jin Ju Kim; Young Min Choi; Soo Jin Chae; Kyu Ri Hwang; Sang Ho Yoon; Min Jeong Kim; Sun Mie Kim; Seung Yup Ku; Seok Hyun Kim; Jung Gu Kim
- Abstract
Objective: To investigate: the prevalence of vitamin D deficiency in Korean women with polycystic ovary syndrome (PCOS), and the relationship between vitamin D status and clinical or metabolic features in this group. Methods: We recruited 38 women with PCOS using the Rotterdam criteria. A total of 109 premenopausal control women were matched with patients based on age and body mass index. Serum 25-hydroxy vitamin D concentrations less than 20 ng/mL were classified as frank vitamin D deficiency. Since vitamin D may play a significant role in metabolic disturbances in women with PCOS, correlations between clinical or metabolic parameters and vitamin D status were analyzed separately in patients and controls. Results: Women with PCOS showed no differences in the level of 25-hydroxy vitamin D (19.6±6.6 ng/mL in patients vs. 20.1±7.4 ng/mL in controls, respectively, p=0.696) or prevalence of vitamin D deficiency (57.9% in patients vs. 56.5% in controls, respectively, p=0.880). In addition, we did not find any correlations between serum vitamin D level and clinical or metabolic profiles in either PCOS patients or controls. Conclusion: Our study found no differences in the absolute level of serum vitamin D between PCOS patients and matched controls. Prevalence of vitamin D deficiency was equally common among both patients and controls. Additionally, we did not find any correlations between serum vitamin D level and clinical or metabolic profiles, suggesting that the role of vitamin D in the pathogenesis of PCOS is not yet clear.
- Subjects
KOREA; POLYCYSTIC ovary syndrome; VITAMIN D deficiency; POLYCYSTIC ovary syndrome treatment; CONTROL groups; PATIENTS
- Publication
Clinical & Experimental Reproductive Medicine, 2014, Vol 41, Issue 2, p80
- ISSN
2233-8233
- Publication type
Article
- DOI
10.5653/cerm.2014.41.2.80