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- Title
Cover Image.
- Abstract
On the Cover: MRAS variants are associated with a variety of common genetic conditions, including coronary artery disease, Noonan syndrome, or cardiac hypertrophy. It is also involved in metabolic disorders like diabetes, obesity, and dyslipidemia. Apart of its active role in diseases, MRAS is also a novel stemness marker impacting mouse embryonic stem cell plasticity and Xenopus embryonic cell fate. Recently, it was demonstrated that MRAS risk variants are specific to smooth muscle cell (SMC) behavior by Shah et al.; Article first published: 22 Jan 2024; https://doi.org/10.1002/iub.2805
- Subjects
CARDIAC hypertrophy; NOONAN syndrome; METABOLIC disorders; CORONARY artery disease; MUSCLE cells; EMBRYONIC stem cells
- Publication
IUBMB Life, 2024, Vol 76, Issue 6, p1
- ISSN
1521-6543
- Publication type
Article
- DOI
10.1002/iub.2746