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Activating STAT3 mutations in CD8+ T-cells correlate to serological positivity in rheumatoid arthritis.
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1466276
By:
- Moosic, Katharine B.;
- Olson, Thomas L.;
- Freijat, Mark;
- Khalique, Samara;
- Hamele, Cait E.;
- Shemo, Bryna;
- Boodoo, Jesse;
- Baker, William;
- Khurana, Gitanjali;
- Schmachtenberg, Matthew;
- Duffy, Tristin;
- Ratan, Aakrosh;
- Darrah, Erika;
- Andrade, Felipe;
- Jones, Marieke;
- Olson, Kristine C.;
- Feith, David J.;
- Kimpel, Donald L.;
- Loughran Jr, Thomas P.
Publication type:
Article
Anti–Peptidylarginine Deiminase 4 Autoantibodies and Disease Duration as Predictors of Treatment Response in Rheumatoid Arthritis.
Published in:
ACR Open Rheumatology, 2024, v. 6, n. 2, p. 81, doi. 10.1002/acr2.11630
By:
- Cappelli, Laura C.;
- Hines, David;
- Wang, Hong;
- Bingham, Clifton O.;
- Darrah, Erika
Publication type:
Article
Patients with checkpoint inhibitor‐induced inflammatory arthritis do not become seropositive for anti‐cyclic citrullinated peptide when followed over time.
Published in:
ACR Open Rheumatology, 2022, v. 4, n. 1, p. 83, doi. 10.1002/acr2.11363
By:
- Cappelli, Laura C.;
- Darrah, Erika;
- Shah, Ami A.;
- Bingham, Clifton O.
Publication type:
Article
Soluble Markers of Antibody Secreting Cell Function as Predictors of Infection Risk in Rheumatoid Arthritis.
Published in:
2019
By:
- Gutierrez, Maria J.;
- Desiderio, Stephen V.;
- Wang, Nae-Yuh;
- Darrah, Erika;
- Cappelli, Laura;
- Nino, Gustavo;
- Jones, Michelle;
- Bingham, Clifton O.;
- Bingham, Clifton O 3rd
Publication type:
journal article
Citrullination modulates antigen processing and presentation by revealing cryptic epitopes in rheumatoid arthritis.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36620-y
By:
- Curran, Ashley M.;
- Girgis, Alexander A.;
- Jang, Yura;
- Crawford, Jonathan D.;
- Thomas, Mekha A.;
- Kawalerski, Ryan;
- Coller, Jeff;
- Bingham III, Clifton O.;
- Na, Chan Hyun;
- Darrah, Erika
Publication type:
Article
Affinity maturation generates pathogenic antibodies with dual reactivity to DNase1L3 and dsDNA in systemic lupus erythematosus.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37083-x
By:
- Gomez-Bañuelos, Eduardo;
- Yu, Yikai;
- Li, Jessica;
- Cashman, Kevin S.;
- Paz, Merlin;
- Trejo-Zambrano, Maria Isabel;
- Bugrovsky, Regina;
- Wang, Youliang;
- Chida, Asiya Seema;
- Sherman-Baust, Cheryl A.;
- Ferris, Dylan P.;
- Goldman, Daniel W.;
- Darrah, Erika;
- Petri, Michelle;
- Sanz, Iñaki;
- Andrade, Felipe
Publication type:
Article
Citrullination modulates antigen processing and presentation by revealing cryptic epitopes in rheumatoid arthritis.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36620-y
By:
- Curran, Ashley M.;
- Girgis, Alexander A.;
- Jang, Yura;
- Crawford, Jonathan D.;
- Thomas, Mekha A.;
- Kawalerski, Ryan;
- Coller, Jeff;
- Bingham III, Clifton O.;
- Na, Chan Hyun;
- Darrah, Erika
Publication type:
Article
Smoking is not linked to the development of anti-peptidylarginine deiminase 4 autoantibodies in rheumatoid arthritis.
Published in:
Arthritis Research & Therapy, 2018, v. 20, n. 1, p. 1, doi. 10.1186/s13075-018-1533-z
By:
- Cappelli, Laura C.;
- Konig, Maximilian F.;
- Gelber, Allan C.;
- Bingham III, Clifton O.;
- Darrah, Erika
Publication type:
Article
Association of anti-peptidyl arginine deiminase antibodies with radiographic severity of rheumatoid arthritis in African Americans.
Published in:
Arthritis Research & Therapy, 2016, v. 18, p. 1, doi. 10.1186/s13075-016-1126-7
By:
- Navarro-Millán, Iris;
- Darrah, Erika;
- Westfall, Andrew O.;
- Mikuls, Ted R.;
- Reynolds, Richard J.;
- Danila, Maria I.;
- Curtis, Jeffrey R.;
- Rosen, Antony;
- Bridges Jr, S. Louis
Publication type:
Article
Rheumatoid Arthritis-Associated Mechanisms of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans.
Published in:
Journal of Clinical Medicine, 2019, v. 8, n. 9, p. 1309, doi. 10.3390/jcm8091309
By:
- Gómez-Bañuelos, Eduardo;
- Mukherjee, Amarshi;
- Darrah, Erika;
- Andrade, Felipe
Publication type:
Article
Distorted Immunodominance by Linker Sequences or other Epitopes from a Second Protein Antigen During Antigen-Processing.
Published in:
Scientific Reports, 2017, p. 46418, doi. 10.1038/srep46418
By:
- Kim, AeRyon;
- Boronina, Tatiana N.;
- Cole, Robert N.;
- Darrah, Erika;
- Sadegh-Nasseri, Scheherazade
Publication type:
Article
Autoantibodies to Peptidylarginine Deiminase 2 Are Associated With Less Severe Disease in Rheumatoid Arthritis.
Published in:
Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.02696
By:
- Darrah, Erika;
- Giles, Jon T.;
- Davis, Ryan L.;
- Naik, Pooja;
- Wang, Hong;
- Konig, Maximilian F.;
- Cappelli, Laura C.;
- Bingham III, Clifton O.;
- Danoff, Sonye K.;
- Andrade, Felipe
Publication type:
Article
Peptidylarginine Deiminase 2 Autoantibodies Are Linked to Less Severe Disease in Multiple Sclerosis and Post-treatment Lyme Disease.
Published in:
Frontiers in Neurology, 2022, v. 13, p. 1, doi. 10.3389/fneur.2022.874211
By:
- Kim, Yaewon;
- Rebman, Alison W.;
- Johnson, Tory P.;
- Wang, Hong;
- Yang, Ting;
- Colantuoni, Carlo;
- Bhargava, Pavan;
- Levy, Michael;
- Calabresi, Peter A.;
- Aucott, John N.;
- Soloski, Mark J.;
- Darrah, Erika
Publication type:
Article
Association of Cross-Reactive Antibodies Targeting Peptidyl-Arginine Deiminase 3 and 4 with Rheumatoid Arthritis-Associated Interstitial Lung Disease.
Published in:
PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0098794
By:
- Giles, Jon T.;
- Darrah, Erika;
- Danoff, Sonye;
- Johnson, Cheilonda;
- Andrade, Felipe;
- Rosen, Antony;
- Bathon, Joan M.
Publication type:
Article
Insights into the study and origin of the citrullinome in rheumatoid arthritis.
Published in:
Immunological Reviews, 2020, v. 294, n. 1, p. 133, doi. 10.1111/imr.12834
By:
- Fert‐Bober, Justyna;
- Darrah, Erika;
- Andrade, Felipe
Publication type:
Article
Immune checkpoint inhibitor–induced inflammatory arthritis as a model of autoimmune arthritis.
Published in:
Immunological Reviews, 2020, v. 294, n. 1, p. 106, doi. 10.1111/imr.12832
By:
- Cappelli, Laura C.;
- Thomas, Mekha A.;
- Bingham, Clifton O.;
- Shah, Ami A.;
- Darrah, Erika
Publication type:
Article
Clinical Utility of Antipeptidyl Arginine Deiminase Type 4 Antibodies.
Published in:
2019
By:
- DARRAH, ERIKA;
- MARTINEZ-PRAT, LAURA;
- MAHLER, MICHAEL
Publication type:
Letter
Spontaneous Secretion of the Citrullination Enzyme PAD2 and Cell Surface Exposure of PAD4 by Neutrophils.
Published in:
Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01200
By:
- Yebin Zhou;
- Bo Chen;
- Mittereder, Nanette;
- Chaerkady, Raghothama;
- Strain, Martin;
- Ling-Ling An;
- Rahman, Saifur;
- Wenting Ma;
- Choon Pei Low;
- Chan, Denice;
- Neal, Frances;
- Bingham III, Clifton O.;
- Sampson, Kevon;
- Darrah, Erika;
- Siegel, Richard M.;
- Hasni, Sarfaraz;
- Andrade, Felipe;
- Vousden, Katherine A.;
- Mustelin, Tomas;
- Sims, Gary P.
Publication type:
Article
Immune-Mediated Pore-Forming Pathways Induce Cellular Hypercitrullination and Generate Citrullinated Autoantigens in Rheumatoid Arthritis.
Published in:
Science Translational Medicine, 2013, v. 5, n. 209, p. 1, doi. 10.1126/scitranslmed.3006869
By:
- Romero, Violeta;
- Fert-Bober, Justyna;
- Nigrovic, Peter A.;
- Darrah, Erika;
- Haque, Uzma J.;
- Lee, David M.;
- van Eyk, Jennifer;
- Rosen, Antony;
- Andrade, Felipe
Publication type:
Article
Erosive Rheumatoid Arthritis Is Associated with Antibodies That Activate PAD4 by Increasing Calcium Sensitivity.
Published in:
Science Translational Medicine, 2013, v. 5, n. 186, p. 1, doi. 10.1126/scitranslmed.3005370
By:
- Darrah, Erika;
- Giles, Jon T.;
- Ols, Michelle L.;
- Bull, Herbert G.;
- Andrade, Felipe;
- Rosen, Antony
Publication type:
Article
Citrulline Not a Major Determinant in the Recognition of Peptidylarginine Deiminase 2 and 4 by Autoantibodies in Rheumatoid Arthritis.
Published in:
Arthritis & Rheumatology, 2020, v. 72, n. 9, p. 1476, doi. 10.1002/art.41276
By:
- Darrah, Erika;
- Davis, Ryan L.;
- Curran, Ashley M.;
- Naik, Pooja;
- Chen, Ruiqiang;
- Na, Chan Hyun;
- Giles, Jon T.;
- Andrade, Felipe
Publication type:
Article
Definition of Naturally Processed Peptides Reveals Convergent Presentation of Autoantigenic Topoisomerase I Epitopes in Scleroderma.
Published in:
Arthritis & Rheumatology, 2020, v. 72, n. 8, p. 1375, doi. 10.1002/art.41248
By:
- Tiniakou, Eleni;
- Fava, Andrea;
- McMahan, Zsuzsanna H.;
- Guhr, Tara;
- O'Meally, Robert N.;
- Shah, Ami A.;
- Wigley, Fredrick M.;
- Cole, Robert N.;
- Boin, Francesco;
- Darrah, Erika
Publication type:
Article
Generation of Distinct Patterns of Rheumatoid Arthritis Autoantigens by Peptidylarginine Deiminase Types 2 and 4 During Perforin‐Induced Cell Damage.
Published in:
Arthritis & Rheumatology, 2020, v. 72, n. 6, p. 912, doi. 10.1002/art.41196
By:
- Romero, Violeta;
- Darrah, Erika;
- Andrade, Felipe
Publication type:
Article
Association of Baseline Peptidylarginine Deiminase 4 Autoantibodies With Favorable Response to Treatment Escalation in Rheumatoid Arthritis.
Published in:
Arthritis & Rheumatology, 2019, v. 71, n. 5, p. 696, doi. 10.1002/art.40791
By:
- Darrah, Erika;
- Yu, Fang;
- Cappelli, Laura C.;
- Rosen, Antony;
- O'Dell, James R.;
- Mikuls, Ted R.
Publication type:
Article
Editorial: Citrullination, and Carbamylation, and Malondialdehyde-Acetaldehyde! Oh My! Entering the Forest of Autoantigen Modifications in Rheumatoid Arthritis.
Published in:
Arthritis & Rheumatology, 2015, v. 67, n. 3, p. 604, doi. 10.1002/art.38970
By:
- Darrah, Erika;
- Andrade, Felipe
Publication type:
Article
Insights Into the Significance of Peptidylarginine Deiminase 4 and Antibodies Against Citrullinated Antigens in the Absence of 'True ACPAs' in an Experimental Model of Arthritis: Comment on the Article by Shelef et al.
Published in:
Arthritis & Rheumatology, 2014, v. 66, n. 9, p. 2642, doi. 10.1002/art.38719
By:
- Konig, Maximilian F.;
- Darrah, Erika;
- Andrade, Felipe
Publication type:
Article
Intersection Between Large Granular Lymphocyte Leukemia and Rheumatoid Arthritis.
Published in:
Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.869205
By:
- Moosic, Katharine B.;
- Ananth, Kusuma;
- Andrade, Felipe;
- Feith, David J.;
- Darrah, Erika;
- Loughran Jr, Thomas P.
Publication type:
Article
NETs: the missing link between cell death and systemic autoimmune diseases?
Published in:
Frontiers in Immunology, 2013, v. 4, p. 1, doi. 10.3389/fimmu.2012.00428
By:
- Darrah, Erika;
- Andrade, Felipe
Publication type:
Article
NETs: The missing link between cell death and systemic autoimmune diseases?
Published in:
Frontiers in Immunology, 2012, v. 3, p. 1, doi. 10.3389/fimmu.2012.00428
By:
- Darrah, Erika;
- Andrade, Felipe
Publication type:
Article
Anti-peptidylarginine deiminase-4 antibodies at mucosal sites can activate peptidylarginine deiminase-4 enzyme activity in rheumatoid arthritis.
Published in:
Arthritis Research & Therapy, 2021, v. 23, n. 1, p. 1, doi. 10.1186/s13075-021-02528-5
By:
- Demoruelle, M. Kristen;
- Wang, Hong;
- Davis, Ryan L.;
- Visser, Ashley;
- Hoang, Johnny;
- Norris, Jill M.;
- Holers, V. Michael;
- Deane, Kevin D.;
- Darrah, Erika
Publication type:
Article
Anti-peptidylarginine deiminase-4 antibodies at mucosal sites can activate peptidylarginine deiminase-4 enzyme activity in rheumatoid arthritis.
Published in:
Arthritis Research & Therapy, 2021, v. 23, n. 1, p. 1, doi. 10.1186/s13075-021-02528-5
By:
- Demoruelle, M. Kristen;
- Hong Wang;
- Davis, Ryan L.;
- Visser, Ashley;
- Hoang, Johnny;
- Norris, Jill M.;
- Holers, V. Michael;
- Deane, Kevin D.;
- Darrah, Erika
Publication type:
Article

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