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- Title
Acetaminophen Use in Pregnant Women and Their Neonates: Safe or Unsafe till Proven Otherwise?
- Authors
van den Anker, John N.; Allegaert, Karel
- Abstract
In his commentary, Dr. Ola Saugstad tries to convince the readers of the journal that the replacement of acetylsalicylic acid with acetaminophen in the early 1980s has resulted in a sharp increase in autism spectrum disorder (ASD) in the USA. Is it the higher exposure to acetaminophen and its metabolites that "causes" ASD/ADHD or is the fact that you are going to develop ASD/ADHD the reason why you have a different clearance of acetaminophen? There is some evidence that supports the fact that kids with ASD/ADHD indeed have a different metabolism of acetaminophen and perhaps, as a consequence, have an elevated risk of adverse events if exposed to acetaminophen [[15]].
- Subjects
PREGNANT women; ACETAMINOPHEN; MEDICAL personnel; NEURODEVELOPMENTAL treatment for infants; NEWBORN infants; DRUG side effects
- Publication
Neonatology (16617800), 2020, Vol 117, Issue 2, p249
- ISSN
1661-7800
- Publication type
Article
- DOI
10.1159/000506837