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- Title
Irradiation of localized squamous cell carcinoma of the nasal vestibule.
- Authors
Vanneste, Ben G. L.; Lopez–Yurda, Marta; Tan, I. Bing; Balm, Alfons J. M.; Borst, Gerben R.; Rasch, Coen R.
- Abstract
Background The purpose of this study was to evaluate the long-term results of primary radiotherapy treatment for squamous cell carcinoma (SCC) of the nasal vestibule. Methods Eighty-one patients were treated with external beam radiotherapy (EBRT) and/or interstitial radiotherapy (IRT) for a primary, localized, Wang classified SCC of the nasal vestibule. Results Median follow-up was 38 months. T1 tumors were treated with IRT: we observed 1 local failure (at 13 months) among 48 patients (5-year local control rate of 97%). Most T2 tumors (20 of 26) were treated with EBRT. There were 8 local recurrences among 26 patients (5-year local control rate of 68%). For the T3 tumors ( n = 7; all treated with EBRT), we observed local recurrence in 2 patients (5-year local control rate of 53%). The late-term side effects were relatively mild. Conclusion Local primary radiotherapy (either IRT for T1 or EBRT for T2/3) is an adequate treatment for SCC of the nasal vestibule with little late sequelae. © 2015 Wiley Periodicals, Inc. Head Neck 38: E1870-E1875, 2016
- Subjects
NASAL cavity cancer; SQUAMOUS cell carcinoma; CANCER radiotherapy research; CANCER relapse; RADIOTHERAPY complications; CANCER treatment; THERAPEUTICS; CANCER risk factors
- Publication
Head & Neck, 2016, Vol 38, pE1870
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.24337