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- Title
Differential diagnoses of solitary and multiple pigmented lesions of the oral mucosa: Evaluation of 905 specimens submitted to histopathological examination.
- Authors
Tavares, Thalita Soares; Da Costa, Adriana Aparecida Silva; Aguiar, Maria Cássia Ferreira; Loyola, Adriano Mota; Barcelos, Natália Santos; Abreu, Mauro Henrique Nogueira Guimarães; Mesquita, Ricardo Alves; Tarquínio, Sandra Beatriz Chaves; De Moraes, Êmile; Vasconcelos, Ana Carolina Uchôa; Costa, Nádia Lago; Mendonça, Elismauro Francisco; Cardoso, Sérgio Vitorino; Nonaka, Cassiano Franscisco Weege; Andrade, Allany de Oliveira; Johann, Aline Cristina Batista Rodrigues; Michels, Arieli Carini; Libório‐Kimura, Tatiana Nayara; Neto, Gerson Oliveira Paiva; Caldeira, Patrícia Carlos
- Abstract
Background: The aim was to analyze the frequency, clinical and demographic features of solitary and multiple/diffuse oral pigmented lesions submitted to histopathological examination, and to summarize the features that guide the clinical differential diagnosis. Methods: Clinical and demographic data were retrieved from biopsy records and descriptive statistics were performed. Results: Nine hundred and five (0.51%) oral pigmented lesions were retrieved among 177 356 specimens, being 95.9% solitary and 4.1% multiple/diffuse lesions. Regardless the overlapping clinical presentation, age, site, association with amalgam restoration, and a nodular appearance may help in the clinical differential diagnosis of solitary oral pigmentations. Patient's habits, site, and systemic signs and symptoms are helpful in the clinical differential diagnosis of multiple/diffuse lesions. Conclusions: Oral pigmented lesions are a rare diagnosis in oral pathology and solitary lesions are more commonly submitted to biopsy. Some key features help in the differential diagnosis, though biopsy can be warranted in doubtful cases.
- Subjects
ORAL mucosa; HISTOPATHOLOGY; DIFFERENTIAL diagnosis; DIAGNOSIS; SYMPTOMS; SYNOVITIS
- Publication
Head & Neck, 2021, Vol 43, Issue 12, p3775
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.26872