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- Title
Electrochemical sensing platform based on screen-printed carbon electrode modified with plasma polymerized acrylonitrile nanofilms for determination of bupropion.
- Authors
Madej, Maria; Trzcińska, Agata; Lipińska, Justyna; Kapica, Ryszard; Fronczak, Maciej; Porada, Radosław; Kochana, Jolanta; Baś, Bogusław; Tyczkowski, Jacek
- Abstract
A original electrochemical sensing platform, based on screen-printed electrodes modification with plasma polymerized acrylonitrile (pp-AN) nanofilms is proposed. For that purpose, plasma-enhanced chemical vapor deposition (PECVD) process was conducted in a parallel plate (13.56 MHz) plasma reactor for 2 min with discharge power of 10 W. The surface topography and electrochemical properties of prepared sensors were investigated by X-ray photoelectron spectroscopy, scanning electron microscopy, energy dispersion spectroscopy, electrochemical impedance spectroscopy, and cyclic voltammetry. The electrochemical characteristics of pp-AN/SPCE and pp-AN/SPAuE sensors was investigated for model redox pair [Fe(CN)6]4−/3−. Conducted research confirmed the excellent chemical stability, durability, wide potential window, high signal-to-noise (S/N) ratio, and, most importantly, the ability to standardize the sensors. The pp-AN/SPCE sensor was applied to the determination of bupropion, an antidepressant drug whose intake has increased dramatically during the COVID-19 pandemic. The voltammetric response of pp-AN/SPCE for BUP was linear in two concentration ranges of 0.63–10.0 and 10.0–50.0 μmol L−1, with a detection limit of 0.21 μmol L−1. Satisfactory recoveries (96.2–102%) and good precision (RSD below 4.1%) obtained for environmental and biological samples confirmed the usefulness of the sensor for the analysis of various kinds of samples.
- Subjects
CARBON electrodes; PLASMA electrodes; PLASMA-enhanced chemical vapor deposition; ACRYLONITRILE; NANOFILMS; ENERGY harvesting; DEIONIZATION of water
- Publication
Microchimica Acta, 2023, Vol 190, Issue 10, p1
- ISSN
0026-3672
- Publication type
Article
- DOI
10.1007/s00604-023-05971-0