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Human bronchial epithelial cell‐derived extracellular vesicle therapy for pulmonary fibrosis via inhibition of TGF‐β‐WNT crosstalk.
Published in:
Journal of Extracellular Vesicles, 2021, v. 10, n. 10, p. 1, doi. 10.1002/jev2.12124
By:
- Kadota, Tsukasa;
- Fujita, Yu;
- Araya, Jun;
- Watanabe, Naoaki;
- Fujimoto, Shota;
- Kawamoto, Hironori;
- Minagawa, Shunsuke;
- Hara, Hiromichi;
- Ohtsuka, Takashi;
- Yamamoto, Yusuke;
- Kuwano, Kazuyoshi;
- Ochiya, Takahiro
Publication type:
Article
Risk factors of postoperative pulmonary complications in patients with asthma and COPD.
Published in:
2018
By:
- Numata, Takanori;
- Nakayama, Katsutoshi;
- Fujii, Satoko;
- Yumino, Yoko;
- Saito, Nayuta;
- Yoshida, Masahiro;
- Kurita, Yusuke;
- Kobayashi, Kenji;
- Ito, Saburo;
- Utsumi, Hirofumi;
- Yanagisawa, Haruhiko;
- Hashimoto, Mitsuo;
- Wakui, Hiroshi;
- Minagawa, Shunsuke;
- Ishikawa, Takeo;
- Hara, Hiromichi;
- Araya, Jun;
- Kaneko, Yumi;
- Kuwano, Kazuyoshi
Publication type:
journal article
Detection of pathogens by real-time PCR in adult patients with acute exacerbation of bronchial asthma.
Published in:
2017
By:
- Yutaka Yoshii;
- Kenichiro Shimizu;
- Miyuki Morozumi;
- Naoko Chiba;
- Kimiko Ubukata;
- Hironori Uruga;
- Shigeo Hanada;
- Hiroshi Wakui;
- Shunsuke Minagawa;
- Hiromichi Hara;
- Takanori Numata;
- Keisuke Saito;
- Jun Araya;
- Katsutoshi Nakayama;
- Kazuma Kishi;
- Kazuyoshi Kuwano;
- Yoshii, Yutaka;
- Shimizu, Kenichiro;
- Morozumi, Miyuki;
- Chiba, Naoko
Publication type:
journal article
Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β.
Published in:
2011
By:
- Kitamura, Hideya;
- Cambier, Stephanie;
- Somanath, Sangeeta;
- Barker, Tyren;
- Minagawa, Shunsuke;
- Markovics, Jennifer;
- Goodsell, Amanda;
- Publicover, Jean;
- Reichardt, Louis;
- Jablons, David;
- Wolters, Paul;
- Hill, Arthur;
- Marks, James D.;
- Jianlong Lou;
- Pittet, Jean-Francois;
- Gauldie, Jack;
- Baron, Jody Lynn;
- Nishimura, Stephen L.;
- Lou, Jianlong
Publication type:
journal article
Pathogens in COPD exacerbations identified by comprehensive real-time PCR plus older methods.
Published in:
International Journal of COPD, 2015, p. 2009, doi. 10.2147/COPD.S82752
By:
- Kenichiro Shimizu;
- Yutaka Yoshii;
- Miyuki Morozumi;
- Naoko Chiba;
- Kimiko Ubukata;
- Hironori Uruga;
- Shigeo Hanada;
- Nayuta Saito;
- Tsukasa Kadota;
- Saburo Ito;
- Hiroshi Wakui;
- Naoki Takasaka;
- Shunsuke Minagawa;
- Jun Kojima;
- Hiromichi Hara;
- Takanori Numata;
- Makoto Kawaishi;
- Keisuke Saito;
- Jun Araya;
- Yumi Kaneko
Publication type:
Article
Metformin attenuates lung fibrosis development via NOX4 suppression.
Published in:
Respiratory Research, 2016, v. 17, p. 1, doi. 10.1186/s12931-016-0420-x
By:
- Nahoko Sato;
- Naoki Takasaka;
- Masahiro Yoshida;
- Kazuya Tsubouchi;
- Shunsuke Minagawa;
- Jun Araya;
- Nayuta Saito;
- Yu Fujita;
- Yusuke Kurita;
- Kenji Kobayashi;
- Saburo Ito;
- Hiromichi Hara;
- Tsukasa Kadota;
- Haruhiko Yanagisawa;
- Mitsuo Hashimoto;
- Hirofumi Utsumi;
- Hiroshi Wakui;
- Jun Kojima;
- Takanori Numata;
- Yumi Kaneko
Publication type:
Article
Efficacy of benralizumab for patients with severe eosinophilic asthma: a retrospective, real-life study.
Published in:
2020
By:
- Numata, Takanori;
- Miyagawa, Hanae;
- Nishioka, Saiko;
- Okuda, Keitaro;
- Utsumi, Hirofumi;
- Hashimoto, Mitsuo;
- Minagawa, Shunsuke;
- Ishikawa, Takeo;
- Hara, Hiromichi;
- Araya, Jun;
- Kuwano, Kazuyoshi
Publication type:
journal article
Efficacy of benralizumab for patients with severe eosinophilic asthma: a retrospective, real-life study.
Published in:
BMC Pulmonary Medicine, 2020, v. 20, n. 1, p. 1, doi. 10.1186/s12890-020-01248-x
By:
- Numata, Takanori;
- Miyagawa, Hanae;
- Nishioka, Saiko;
- Okuda, Keitaro;
- Utsumi, Hirofumi;
- Hashimoto, Mitsuo;
- Minagawa, Shunsuke;
- Ishikawa, Takeo;
- Hara, Hiromichi;
- Araya, Jun;
- Kuwano, Kazuyoshi
Publication type:
Article
Successful treatment of steroid-refractory immune checkpoint inhibitor-related pneumonitis with triple combination therapy: a case report.
Published in:
Cancer Immunology, Immunotherapy, 2020, v. 69, n. 10, p. 2033, doi. 10.1007/s00262-020-02600-0
By:
- Utsumi, Hirofumi;
- Araya, Jun;
- Okuda, Keitaro;
- Watanabe, Junko;
- Takekoshi, Daisuke;
- Fujita, Yu;
- Hashimoto, Mitsuo;
- Wakui, Hiroshi;
- Minagawa, Shunsuke;
- Numata, Takanori;
- Hara, Hiromichi;
- Kuwano, Kazuyoshi
Publication type:
Article
Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10991-7
By:
- Yoshida, Masahiro;
- Minagawa, Shunsuke;
- Araya, Jun;
- Sakamoto, Taro;
- Hara, Hiromichi;
- Tsubouchi, Kazuya;
- Hosaka, Yusuke;
- Ichikawa, Akihiro;
- Saito, Nayuta;
- Kadota, Tsukasa;
- Sato, Nahoko;
- Kurita, Yusuke;
- Kobayashi, Kenji;
- Ito, Saburo;
- Utsumi, Hirohumi;
- Wakui, Hiroshi;
- Numata, Takanori;
- Kaneko, Yumi;
- Mori, Shohei;
- Asano, Hisatoshi
Publication type:
Article
Prostaglandin E-Major Urinary Metabolite (PGE-MUM) as a Tumor Marker for Lung Adenocarcinoma.
Published in:
Cancers, 2019, v. 11, n. 6, p. 768, doi. 10.3390/cancers11060768
By:
- Kawamoto, Hironori;
- Hara, Hiromichi;
- Araya, Jun;
- Ichikawa, Akihiro;
- Fujita, Yu;
- Utsumi, Hirofumi;
- Hashimoto, Mitsuo;
- Wakui, Hiroshi;
- Minagawa, Shunsuke;
- Numata, Takanori;
- Arihiro, Seiji;
- Matsuura, Tomokazu;
- Fujiwara, Mutsunori;
- Ito, Satoru;
- Kuwano, Kazuyoshi
Publication type:
Article
Long-Term Efficacy and Clinical Remission After Benralizumab Treatment in Patients with Severe Eosinophilic Asthma: A Retrospective Study.
Published in:
Journal of Asthma & Allergy, 2022, v. 15, p. 1731, doi. 10.2147/JAA.S391807
By:
- Numata, Takanori;
- Araya, Jun;
- Okuda, Keitaro;
- Miyagawa, Hanae;
- Minagawa, Shunsuke;
- Ishikawa, Takeo;
- Hara, Hiromichi;
- Kuwano, Kazuyoshi
Publication type:
Article
Real-World Effectiveness of Dupilumab for Patients with Severe Asthma: A Retrospective Study.
Published in:
Journal of Asthma & Allergy, 2022, v. 15, p. 395, doi. 10.2147/JAA.S357548
By:
- Numata, Takanori;
- Araya, Jun;
- Miyagawa, Hanae;
- Okuda, Keitaro;
- Takekoshi, Daisuke;
- Hashimoto, Mitsuo;
- Minagawa, Shunsuke;
- Ishikawa, Takeo;
- Hara, Hiromichi;
- Kuwano, Kazuyoshi
Publication type:
Article
Effectiveness of Switching Biologics for Severe Asthma Patients in Japan: A Single-Center Retrospective Study.
Published in:
Journal of Asthma & Allergy, 2021, v. 14, p. 609, doi. 10.2147/JAA.S311975
By:
- Numata, Takanori;
- Araya, Jun;
- Miyagawa, Hanae;
- Okuda, Keitaro;
- Fujita, Yu;
- Utsumi, Hirofumi;
- Takekoshi, Daisuke;
- Hashimoto, Mitsuo;
- Minagawa, Shunsuke;
- Ishikawa, Takeo;
- Hara, Hiromichi;
- Kuwano, Kazuyoshi
Publication type:
Article
Possible relationship between esophageal dilatation and severity of M. abscessus pulmonary disease.
Published in:
PLoS ONE, 2021, v. 16, n. 12, p. 1, doi. 10.1371/journal.pone.0261866
By:
- Hara, Hiromichi;
- Okuda, Keitaro;
- Araya, Jun;
- Utsumi, Hirofumi;
- Takekoshi, Daisuke;
- Ito, Saburo;
- Wakui, Hiroshi;
- Minagawa, Shunsuke;
- Numata, Takanori;
- Kuwano, Kazuyoshi
Publication type:
Article
Characteristics of anti-IL-17/23 biologics-induced interstitial pneumonia in patients with psoriasis.
Published in:
PLoS ONE, 2021, v. 16, n. 1, p. 1, doi. 10.1371/journal.pone.0245284
By:
- Miyagawa, Hanae;
- Hara, Hiromichi;
- Araya, Jun;
- Minagawa, Shunsuke;
- Numata, Takanori;
- Umezawa, Yoshinori;
- Asahina, Akihiko;
- Nakagawa, Hidemi;
- Kuwano, Kazuyoshi
Publication type:
Article
Fibroblast-derived Extracellular Vesicles Induce Lung Cancer Progression in the Idiopathic Pulmonary Fibrosis Microenvironment.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2023, v. 69, n. 1, p. 34, doi. 10.1165/rcmb.2022-0253OC
By:
- Yu Fujita;
- Shota Fujimoto;
- Atsushi Miyamoto;
- Reika Kaneko;
- Tsukasa Kadota;
- Naoaki Watanabe;
- Ryusuke Kizawa;
- Hironori Kawamoto;
- Junko Watanabe;
- Hirofumi Utsumi;
- Hiroshi Wakui;
- Shunsuke Minagawa;
- Jun Araya;
- Takashi Ohtsuka;
- Takahiro Ochiya;
- Kazuyoshi Kuwano
Publication type:
Article
Extracellular Vesicles from Fibroblasts Induce Epithelial-Cell Senescence in Pulmonary Fibrosis.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2020, v. 63, n. 5, p. 623, doi. 10.1165/rcmb.2020-0002OC
By:
- Tsukasa Kadota;
- Yusuke Yoshioka;
- Yu Fujita;
- Jun Araya;
- Shunsuke Minagawa;
- Hiromichi Hara;
- Atsushi Miyamoto;
- Souichiro Suzuki;
- Sakashi Fujimori;
- Tadasu Kohno;
- Takeshi Fujii;
- Kazuma Kishi;
- Kazuyoshi Kuwano;
- Takahiro Ochiya
Publication type:
Article
Regulated Necrosis in Pulmonary Disease: A Focus on Necroptosis and Ferroptosis.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2020, v. 62, n. 5, p. 554, doi. 10.1165/rcmb.2019-0337TR
By:
- Shunsuke Minagawa;
- Masahiro Yoshida;
- Jun Araya;
- Hiromichi Hara;
- Hirotaka Imai;
- Kazuyoshi Kuwano
Publication type:
Article
Involvement of Alveolar Epithelial Cell Necroptosis in Idiopathic Pulmonary Fibrosis Pathogenesis.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2018, v. 59, n. 2, p. 215, doi. 10.1165/rcmb.2017-0034OC
By:
- Ji-Min Lee;
- Masahiro Yoshida;
- Mi-So Kim;
- June-Hyuk Lee;
- Ae-Rin Baek;
- An Soo Jang;
- Do Jin Kim;
- Shunsuke Minagawa;
- Su Sie Chin;
- Choon-Sik Park;
- Kazuyoshi Kuwano;
- Sung Woo Park;
- Jun Araya
Publication type:
Article
Pirfenidone inhibits myofibroblast differentiation and lung fibrosis development during insufficient mitophagy.
Published in:
2017
By:
- Yusuke Kurita;
- Jun Araya;
- Shunsuke Minagawa;
- Hiromichi Hara;
- Akihiro Ichikawa;
- Nayuta Saito;
- Tsukasa Kadota;
- Kazuya Tsubouchi;
- Nahoko Sato;
- Masahiro Yoshida;
- Kenji Kobayashi;
- Saburo Ito;
- Yu Fujita;
- Hirofumi Utsumi;
- Haruhiko Yanagisawa;
- Mitsuo Hashimoto;
- Hiroshi Wakui;
- Yutaka Yoshii;
- Takeo Ishikawa;
- Takanori Numata
Publication type:
journal article
Effect of anti‐interleukin‐17 biologics on Krebs von den Lungen‐6 level in patients with psoriasis.
Published in:
Journal of Dermatology, 2021, v. 48, n. 6, p. 886, doi. 10.1111/1346-8138.15895
By:
- Hara, Hiromichi;
- Miyagawa, Hanae;
- Araya, Jun;
- Minagawa, Shunsuke;
- Numata, Takanori;
- Umezawa, Yoshinori;
- Asahina, Akihiko;
- Nakagawa, Hidemi;
- Kuwano, Kazuyoshi
Publication type:
Article
Efficacy of mepolizumab for patients with severe asthma and eosinophilic chronic rhinosinusitis.
Published in:
2019
By:
- Numata, Takanori;
- Nakayama, Katsutoshi;
- Utsumi, Hirofumi;
- Kobayashi, Kenji;
- Yanagisawa, Haruhiko;
- Hashimoto, Mitsuo;
- Minagawa, Shunsuke;
- Ishikawa, Takeo;
- Hara, Hiromichi;
- Araya, Jun;
- Kuwano, Kazuyoshi
Publication type:
journal article
Selective Targeting of TGF-β Activation to Treat Fibroinflammatory Airway Disease.
Published in:
Science Translational Medicine, 2014, v. 6, n. 241, p. 1, doi. 10.1126/scitranslmed.3008074
By:
- Shunsuke Minagawa;
- Jianlong Lou;
- Seed, Robert I.;
- Cormier, Anthony;
- Shenping Wu;
- Yifan Cheng;
- Murray, Lynne;
- Ping Tsui;
- Connor, Jane;
- Herbst, Ronald;
- Govaerts, Cedric;
- Barker, Tyren;
- Cambier, Stephanie;
- Haruhiko Yanagisawa;
- Goodsell, Amanda;
- Mitsuo Hashimoto;
- Brand, Oliver J.;
- Ran Cheng;
- Ma, Royce;
- McKnelly, Kate J.
Publication type:
Article
Real-life effectiveness of dupilumab in patients with mild to moderate bronchial asthma comorbid with CRSwNP.
Published in:
2022
By:
- Minagawa, Shunsuke;
- Araya, Jun;
- Watanabe, Naoaki;
- Fujimoto, Shota;
- Watanabe, Junko;
- Hara, Hiromichi;
- Numata, Takanori;
- Kuwano, Kazuyoshi;
- Matsuwaki, Yoshinori
Publication type:
journal article
Involvement of Parkin‐mediated mitophagy in the pathogenesis of chronic obstructive pulmonary disease‐related sarcopenia.
Published in:
Journal of Cachexia, Sarcopenia & Muscle, 2022, v. 13, n. 3, p. 1864, doi. 10.1002/jcsm.12988
By:
- Ito, Akihiko;
- Hashimoto, Mitsuo;
- Tanihata, Jun;
- Matsubayashi, Sachi;
- Sasaki, Ryoko;
- Fujimoto, Shota;
- Kawamoto, Hironori;
- Hosaka, Yusuke;
- Ichikawa, Akihiro;
- Kadota, Tsukasa;
- Fujita, Yu;
- Takekoshi, Daisuke;
- Ito, Sabro;
- Minagawa, Shunsuke;
- Numata, Takanori;
- Hara, Hiromichi;
- Matsuoka, Tatsuki;
- Udaka, Jun;
- Araya, Jun;
- Saito, Mitsuru
Publication type:
Article
Chaperone‐mediated autophagy receptor modulates tumor growth and chemoresistance in non–small cell lung cancer.
Published in:
Cancer Science, 2020, v. 111, n. 11, p. 4154, doi. 10.1111/cas.14629
By:
- Ichikawa, Akihiro;
- Fujita, Yu;
- Hosaka, Yusuke;
- Kadota, Tsukasa;
- Ito, Akihiko;
- Yagishita, Shigehiro;
- Watanabe, Naoaki;
- Fujimoto, Shota;
- Kawamoto, Hironori;
- Saito, Nayuta;
- Yoshida, Masahiro;
- Hashimoto, Mitsuo;
- Minagawa, Shunsuke;
- Hara, Hiromichi;
- Motoi, Noriko;
- Yamamoto, Yusuke;
- Ochiya, Takahiro;
- Araya, Jun;
- Kuwano, Kazuyoshi
Publication type:
Article

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