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- Title
术前血清甲状腺球蛋白检测对甲状腺乳头状癌颈部淋巴结转移的预测价值分析.
- Authors
王依莹; 孔伟; 刘庆华; 邢浩; 尹峰燕; 刘新悦; 何倩; 邢薇佳
- Abstract
Objective The objective of this study was to investigate the relationship between preoperative serum thyroglobulin(PS-Tg)and lymph node metastasis(LNM)in papillary thyroid carcinoma(PTC).Methods This study included 283 clinical and pathological data of PTC patients who underwent thyroidectomy from October 2021 to September 2022 and were confirmed by postoperative pathology.The relationship between PS-Tg and PTC LNM was analyzed by univariable and multivariable logistic regression, the nomogram was used to quantify the relationship between them, and the optimal cut-off value was determined by receiver operating characteristic(ROC)curves.Results The level of PS-Tg in the PTC combined with LNM group was higher than that in the pure PTC group(P<0.05).Univariable and multivariable logistic regression analyses showed that elevated PS-Tg level might be an independent risk factor for LNM of PTC,and the increase of PS-Tg level could explain approximately 15% of the risk of LNM in PTC.Conclusion Elevated PS-Tg level may be a risk factor for cervical LNM in PTC patients, and it has a certain predictive value for preoperative LNM diagnosis.
- Subjects
RISK of metastasis; CERVICAL vertebrae; STATISTICS; PREDICTIVE tests; CONFIDENCE intervals; THYROIDECTOMY; PREOPERATIVE period; THYROID gland tumors; PAPILLARY carcinoma; LYMPH nodes; CHI-squared test; DESCRIPTIVE statistics; TUMOR markers; GLOBULINS; LOGISTIC regression analysis; RECEIVER operating characteristic curves; SPINAL tumors; DISEASE risk factors; DISEASE complications
- Publication
Practical Oncology Journal, 2023, Vol 37, Issue 1, p52
- ISSN
1002-3070
- Publication type
Article
- DOI
10.11904/j.issn.1002-3070.2023.01.009