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- Title
Three-component heterocyclization of 5-(arylmethylidene)pyrimidine-2,4,6(1 H,3 H,5 H)-triones with aldehydes and amino acids.
- Authors
Tyrkov, A.; Yurtaeva, E.; Dan'kova, L.
- Abstract
Previously unknown substituted 4-aryl-2,7,9-triazaspiro[4.5]decane-6,8,10-triones were synthesized in 50-70% yield by heating 5-(arylmethylidene)barbituric acids with N-methyl- or N-phenylglycine and para-formaldehyde or 4-methoxybenzaldehyde in boiling toluene for 14 h.
- Subjects
AROMATIC compound derivatives; TOLUENE; EFFECT of heat on amino acids; FORMALDEHYDE analysis; CHEMICAL amplification; ACETIC acid derivatives; GLYCINE
- Publication
Russian Journal of Organic Chemistry, 2017, Vol 53, Issue 7, p1071
- ISSN
1070-4280
- Publication type
Article
- DOI
10.1134/S1070428017070181