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- Title
What are the appropriate timing and cut‐off values of pancreatic enzymes for predicting postendoscopic retrograde cholangiopancreatography pancreatitis?
- Authors
Kato, Hironari
- Abstract
Postendoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is a common complication of ERCP procedures. The incidence of PEP is relatively low, but it can be fatal if severe. Early diagnosis and treatment are crucial, so researchers have been studying the use of serum pancreatic enzyme levels to predict PEP. A meta-analysis of 20 observational studies found that serum amylase or lipase levels more than three times the upper limit of normal (ULN) measured 2-4 hours after ERCP are useful for predicting PEP. However, there is no consensus on a biomarker that can diagnose PEP earlier than serum pancreatic enzymes. Patient and procedural risk factors can also help predict the onset of PEP. Further research is needed to validate these findings.
- Subjects
PANCREATIC enzymes; PANCREATITIS; DISEASE risk factors
- Publication
Digestive Endoscopy, 2024, Vol 36, Issue 6, p688
- ISSN
0915-5635
- Publication type
Article
- DOI
10.1111/den.14746