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- Title
High-Intensity Interval Versus Moderate-Intensity Continuous Exercise Training on Glycemic Control, Beta Cell Function, and Aerobic Fitness in Women with Type 2 Diabetes.
- Authors
Niyazi, Arghavan; Yasrebi, Seyed Mohammad Ali; Yazdanian, Mohtaram; Mohammad Rahimi, Gholam Rasul
- Abstract
Objective: This study aimed to compare the effects of High-Intensity Interval Training (HIIT) and Moderate-Intensity Continuous Training (MICT) on glycemic control, beta-cell function, and aerobic fitness in women with Type 2 Diabetes Mellitus (T2DM). Methods: Thirty-six women with T2DM were assigned equally to HIIT, MICT, and control (CON) groups. Participants in the exercise cohorts underwent a 12-week training regimen (three sessions per week), while the CON group maintained an inactive lifestyle. Glycaemia variables, beta-cell function, maximal oxygen uptake (VO2max), lipid profiles, and body composition were assessed at baseline and post-intervention. Results: Both HIIT and MICT interventions led to significant improvements in glucose, insulin, HbA1c, and insulin resistance index. Moreover, visceral adiposity index (VAI), lipid accumulation product (LAP), total cholesterol (TC), and low-density lipoprotein (LDL) levels significantly decreased in the HIIT and MICT groups after 12 weeks. Triglyceride (TG) levels decreased only after MICT, while high-density lipoprotein (HDL) levels increased after both interventions. Maximal oxygen uptake (VO2max), body mass, body mass index (BMI), and waist circumference (WC) significantly improved in all exercise groups. Notably, the HIIT group showed greater reductions in body mass compared to MICT. Nevertheless, beta-cell function remained unaltered after these two exercise regimens. Conclusion: Both HIIT and MICT interventions effectively managed T2DM in women, regardless of exercise intensity. The HIIT regimen can be considered for time-efficient lifestyle interventions in people with T2DM.
- Subjects
LIPID analysis; ANALYSIS of triglycerides; BLOOD sugar analysis; EXERCISE physiology; CARDIOPULMONARY fitness; HIGH density lipoproteins; REPEATED measures design; GLYCOSYLATED hemoglobin; ADIPOSE tissues; BODY mass index; COMPUTER software; FOOD consumption; T-test (Statistics); DATA analysis; HIGH-intensity interval training; PANCREATIC beta cells; GLYCEMIC control; EXERCISE therapy; SEDENTARY lifestyles; BODY composition; BLOOD collection; ENZYME-linked immunosorbent assay; INSULIN; RANDOMIZED controlled trials; INSULIN resistance; WAIST circumference; LOW density lipoproteins; PRE-tests &; post-tests; TYPE 2 diabetes; CHOLESTEROL; ONE-way analysis of variance; STATISTICS; WOMEN'S health; OXYGEN consumption; FOOD diaries; DATA analysis software
- Publication
Biological Research for Nursing, 2024, Vol 26, Issue 3, p449
- ISSN
1099-8004
- Publication type
Article
- DOI
10.1177/10998004241239330