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- Title
Digit ratio (2D:4D) as a marker for mental disorders: Low (masculinized) 2D:4D in autism-spectrum disorders, high (feminized) 2D:4D in schizophrenic-spectrum disorders.
- Authors
Voracek, Martin
- Abstract
Augmenting and supplementing the arguments of Crespi & Badcock (C&B), I show that digit ratio (2D:4D), a putative marker of prenatal androgen action, indeed appears differentially altered in autism-spectrum disorders (lower/masculinized) versus schizophrenic-spectrum disorders (higher/feminized). Consistent with C&B's framework, some evidence (substantial heritability, assortative mating, sex-specific familial transmission) points to possible sex chromosome and imprinted genes effects on 2D:4D expression.
- Subjects
MENTAL illness; AUTISM; SCHIZOPHRENIA; PSYCHOSES; ANDROGENS; PATHOLOGICAL psychology; NEUROLOGY
- Publication
Behavioral & Brain Sciences, 2008, Vol 31, Issue 3, p283
- ISSN
0140-525X
- Publication type
Article
- DOI
10.1017/S0140525X08004445