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- Title
A reversible thermoresponsive sealant for temporary closure of ocular trauma.
- Authors
Bayat, Niki; Yi Zhang; Falabella, Paulo; Menefee, Roby; Whalen III, John J.; Humayun, Mark S.; Thompson, Mark E.
- Abstract
The article reports on the use of an injectable, thermoresponsive sealant (TRS) and a custom tool to occlude open globe injuries, which are full-thickness injuries sustained to the eye wall. The TRS consists of physically cross-linked N-isopropylacrylamide copolymerized with butylacrylate. TRS deployment shows significant improvement in wound sealing.
- Subjects
OCULAR injuries; SEALING compounds; OPHTHALMOLOGICAL therapeutics; MEDICAL equipment; HYDROGELS
- Publication
Science Translational Medicine, 2017, Vol 9, Issue 419, p1
- ISSN
1946-6234
- Publication type
Article
- DOI
10.1126/scitranslmed.aan3879