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- Title
Comparison of indirect and direct blood pressure measurements in baboons during ketamine anaesthesia.
- Authors
Yeung, Kristen R.; Lind, Joanne M.; Heffernan, Scott J.; Sunderland, Neroli; Hennessy, Annemarie; Makris, Angela
- Abstract
Background The aim of this study was to assess agreement between different methods of blood pressure measurement in anaesthetised baboons. Methods Systolic and diastolic blood pressure ( SBP and DBP) were measured in anaesthetised baboons using intra-arterial radiotelemetry, automated oscillometry and mercury sphygmomanometry. Correlation between the different methods was assessed. Results The correlation between intra-arterial radiotelemetry and automated oscillometry was 0.9 ( P < 0.001) for SBP and 0.9 ( P < 0.001) for DBP. Between-method differences were −4.4 ± 7.2 mm Hg for SBP and −3.4 ± 7.1 mm Hg for DBP. For automated oscillometry vs. mercury sphygmomanometry, correlation was 0.4 for both SBP ( P < 0.001) and DBP ( P < 0.001). Between-method differences were 7.9 ± 12.7 mm Hg for SBP and 7.3 ± 12.6 mm Hg for DBP. Conclusions Our study demonstrates that automated oscillometry may be an appropriate alternative to telemetry for measuring blood pressure in anaesthetised baboons.
- Subjects
KETAMINE; BABOONS as laboratory animals; BLOOD pressure measurement; CARDIOVASCULAR diseases; MEDICAL statistics; SPHYGMOMANOMETERS; COMPARATIVE studies
- Publication
Journal of Medical Primatology, 2014, Vol 43, Issue 4, p217
- ISSN
0047-2565
- Publication type
Article
- DOI
10.1111/jmp.12113