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- Title
Felty's Syndrome: Favorable Response to Granulocyte-Macrophage Colony-Stimulating Factor in the Acute Phase.
- Authors
Kaiser, U.; Klausmann, M.; Kolb, G.; Pflüger, K.H.; Havemann, K.
- Abstract
We report a case of Felty's syndrome in which infectious complications due to severe neutropenia could be overcome by short-term treatment with recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF, 7 μg/kg/day s.c). Leukocyte counts rose from 1,050/mm3 at presentation to 4,470/mm3 after 15 days of treatment. A flare-up of arthritis was not noted. Defects in granulocyte function and clinical improvement prior to leukocyte rise suggest that the beneficial effect of GM-CSF is mainly due to an improvement of granulocyte function. Copyright © 1992 S. Karger AG, Basel
- Publication
Acta Haematologica, 1992, Vol 87, Issue 4, p190
- ISSN
0001-5792
- Publication type
Article
- DOI
10.1159/000204757