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- Title
Hematological Abnormalities in Scleroderma.
- Authors
Frayha, Rida A.; Shulman, Lowerence E.; Stevens, Mary B.
- Abstract
Hematological abnormalities in scleroderma indicate a specific complication of the disease itself, or an associated illness. Among 180 patients with scleroderma, anemia was detected in 25% and was attributed to chronic inflammatory disease (usually an overlap syndrome), bleeding mucosal telangiectases as part of the CREST syndrome, intestinal malabsorption, and microangiopathic hemolysis. Leukocytosis, present in 14%, was correlated with active myopathy and/or advanced visceral involvement while leukopenia was suggestive of a crossover with systemic lupus erythematosus. Thrombocytopenia was often a manifestation of microangiopathy, and thrombocytosis was associated with an arteritis or a tumor syndrome. Copyright © 1980 S. Karger AG, Basel
- Publication
Acta Haematologica, 1980, Vol 64, Issue 1, p25
- ISSN
0001-5792
- Publication type
Article
- DOI
10.1159/000207206