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- Title
The evaluation of serum brain-derived neurotrophic factor levels in pregnant women with hyperemesis gravidarum.
- Authors
Cendek, Busra Demir; Cakir, Betul Tokgoz; Fındık, Rahime Bedir; Ibanoglu, Mujde Can; Yildirim, Melahat; Celik, Huseyin Tugrul; Yavuz, Ayse Filiz
- Abstract
Objectives: The aim of this study was to investigate the relationship between levels of brain-derived neurotrophic factor (BDNF), which is considered a cause of conditions such as depression and eating disorders, and hyperemesis gravidarum (HG). Material and methods: This study was conducted as a prospective study at Ankara Ataturk Training and Research Hospital in the Department of Obstetrics and Gynecology. The study included 73 pregnant women with singleton pregnancies (32 pregnant women with HG and 41 pregnant women without hyperemesis). Serum BDNF levels were compared between the two groups. Results: The mean age of the study group was 27.3 ± 3.5 years and the body mass index (BMI) was 22.4 ± 2.7 kg/m2. There is no statistically significant difference between the study group and the control group in terms of demographic data (p > 0.05). The pregnant women with HG were found to have significantly higher serum BDNF levels compared to the control group (349.1 ± 94.6 pg/mL vs 292. 3 ± 86.01, p = 0.009) Conclusions: Serum BDNF levels that are low in psychiatric disorders such as depression or anxiety were found as high in pregnant women with HG.
- Subjects
BRAIN-derived neurotrophic factor; SERUM; PREGNANT women; MORNING sickness; BODY mass index
- Publication
Ginekologia Polska, 2023, Vol 94, Issue 11, p913
- ISSN
0017-0011
- Publication type
Article
- DOI
10.5603/GP.a2023.0049