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- Title
Effects of Different Anaesthesia Methods on NTI Index, Mean Arterial Pressure, Heart Rate and S-100β Protein in Elderly Patients Undergoing Abdominal Surgery.
- Authors
XIA, X.; GUO, T.; WANG, L.; YANG, Z.; ZHU, Z.; ZHANG, D.
- Abstract
In order to study the effects of different anaesthesia methods on nearest taxon index, mean arterial pressure, heart rate, S-100β protein and other indicators in elderly patients undergoing abdominal surgery, 127 elderly patients hospitalized for abdominal surgery were selected as the study subjects. According to the degree of anaesthesia, they were divided into 2 groups one received deep anaesthesia and the other shallow anaesthesia. The above mentioned indicators were observed in both groups of patients after surgery, to explore the influence of different anaesthesia methods on elderly patients. There was no statistical difference in basic information between the two groups, while there was statistical difference in nearest taxon index, mean arterial pressure and heart rate between the two groups (p<0.05). Comparing and analysing postoperative cognitive dysfunction, postoperative delirium, mini-mental state examination and clockdrawing tests between the two groups, it was found that there was no statistical difference in the comparison of mini mental state exam and CDT scales alone, but the comprehensive comparison between them was more objective and comprehensive, namely post-operative cognitive dysfunction, with statistical difference (p>0.05). In the analysis of serum S-100β protein in two groups, it was found that deep anaesthesia not only prevented the increase of S-100β protein, but also quickly restored to the initial level. Therefore, through this study, it is found that different depths of anaesthesia has no significant effect on the cognitive function of the elderly, but deep anaesthesia has a lower incidence of post-operative cognitive dysfunction than shallow anaesthesia and can effectively reduce the level of S-100β protein in patients.
- Subjects
HEART beat; ABDOMINAL surgery; OLDER patients; ARTERIAL pressure; ANESTHESIA
- Publication
Indian Journal of Pharmaceutical Sciences, 2019, Vol 81, p79
- ISSN
0250-474X
- Publication type
Article