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- Title
Molecular Research on Plasmodium Infection and Immunity.
- Authors
Coutelier, Jean-Paul; Pied, Sylviane
- Abstract
This document, titled "Molecular Research on Plasmodium Infection and Immunity," discusses the global strategy for malaria reduction set by the World Health Organization (WHO) and the challenges that still exist in achieving this goal. These challenges include mosquito resistance to insecticides, the impact of global warming on mosquito distribution, local reluctance to implement vector control strategies, and the emergence of drug-resistant strains of the Plasmodium parasite. The document also highlights the importance of understanding the biology of the Anopheles mosquito, improving diagnostic methods, and targeting the mechanisms that lead to severe malaria cases. Additionally, it explores the role of host migration in the spread of Plasmodium and the potential for new diagnostic approaches and vaccines. The document concludes by discussing the indirect effects of Plasmodium infection on other diseases and the need for a comprehensive understanding of the epidemiology and pathogenic consequences of the infection.
- Subjects
CEREBRAL malaria; PLASMODIUM; METAGENOMICS; MOSQUITO control; INFECTION; KILLER cells; IMMUNITY; ENDOTOXINS
- Publication
International Journal of Molecular Sciences, 2024, Vol 25, Issue 7, p4133
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms25074133