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- Title
Prion biology: the quest for the test.
- Authors
Aguzzi, Adriano
- Abstract
The article focuses on the medical need for a blood test for prions. Prions is considered as the elusive infectious particles responsible for transmissible spongiforn encephalopathies which is responsible for most tragic disasters in the history of medicine. It has been found out that adaptation of the protein misfolding cyclic amplification assay to use recombinant hamster prion protein as a substrate shows promise for both basic research applications and clinical diagnostic assays.
- Subjects
PRIONS; PROTEINS; CRISIS management; BLOOD testing; MEDICAL research
- Publication
Nature Methods, 2007, Vol 4, Issue 8, p614
- ISSN
1548-7091
- Publication type
Article
- DOI
10.1038/nmeth0807-614