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- Title
Síntomas depresivos en una muestra de mujeres con hipotiroidismo subclínico y su relación con los cloratos del agua del grifo.
- Authors
Pérez-Fernández, María-Reyes; Martínez Lede, Ismael; Fernández Varela, María-Milagros; Fariñas Valiña, Natalia; Calvo Ayuso, Natalia; Rodríguez Garrido, Juan-Imeldo
- Abstract
Introduction: depressive symptoms may develop in subclinical hypothyroidism and their presence usually facilitates recognition and the establishment of replacement treatment; however, recent studies have found no association between the two. Be-sides, thyroid function can be affected by endocrine disruptors and some of them, such as chlorates, can be found in the water we drink. Objectives: to know if the type of water consumed may influence the development of depressive symptoms in patients with subclinical hypothyroidism. Methods: 96 women with subclinical hypothyroidism, without thyroid treatment, par-ticipated from a health area in Spain. We studied, among other variables, the pres-ence of depressive symptoms, type of water consumption (tap, bottled or spring) and the level of chlorates in the tap water. Results: 41.7 % (40) of women presented depressive symptoms and these were relat-ed to the consumption of tap water (p = 0.001), resulting in a reliable predictor (OR, 27.79; p = 0.007). Chlorate level in the tap water was 250 µg/L, a value within the maximum limit allowed by law. Conclusions: chronic exposure to chlorates in water, in women with subclinical hypo-thyroidism, at levels authorized by law, could favor the inhibition of iodine transport and the appearance of depressive symptoms. It would be interesting to test this hy-pothesis as well as its possible effect on other population profiles.
- Subjects
DEPRESSION in women; MENTAL depression; ENDOCRINE disruptors; WATER consumption; WATER levels
- Publication
Nutrición Hospitalaria, 2024, Vol 41, Issue 2, p439
- ISSN
0212-1611
- Publication type
Article
- DOI
10.20960/nh.04919