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- Title
Compromised Defenses: Exploitation of Epithelial Responses During Viral-Bacterial Co-Infection of the Respiratory Tract.
- Authors
Melvin, Jeffrey A.; Bomberger, Jennifer M.
- Abstract
The article presents a study which focuses on the role of the respiratory epithelium in defending against microbial pathogens and in facilitating synergistic pathogenic interactions. The topics discussed include role of the respiratory epithelium in innate and adaptive immunity, the mechanism that drives the increase of bacterial adherence and colonization of viral infection and the skew of direction of immune status of the respiratory tract to predispose to secondary bacterial infection.
- Subjects
RESPIRATORY infections; EPITHELIUM; PATHOGENIC microorganisms; IMMUNE adherence reaction; BACTERIAL diseases
- Publication
PLoS Pathogens, 2016, Vol 12, Issue 9, p1
- ISSN
1553-7366
- Publication type
Article
- DOI
10.1371/journal.ppat.1005797