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- Title
Prescripción de antibióticos en pacientes hospitalizados con COVID-19 en un hospital privado de Caracas: Estudio retrospectivo.
- Authors
Silva, Isabel-Carlota; Guzmán, Manuel; de Oca, María Montes; Bacci, Santiago; de Abreu, Fátima; Villarroel, Héctor; Stulin, Irene; Blanco, Gabriela; Sánchez, Laura; Quevedo, Jennireth; Arvelo, María Cristina; Valera, Nathalia; Papa, Irene; Carlos Catari, Juan; Luis Lopez, José; Moran, Brigitte; Cárdenas, Claudio; Santucci, Saverio; Luis Viloria, José; García, Eleonora
- Abstract
Background: There is little information on the prevalence of bacterial coinfection and use of antibiotics in hospitalized COVID-19 patients. The present study assesses the frequency of in-hospital antibiotic prescription, the bacterial cultures implementation and the clinical characteristics of patients with COVID-19 according to the use of antibiotics. Methods: Retrospective, observational study of hospitalized patients with COVID-19. The ISARIC-WHO form was used for data collection. Results: 145 patients were included, 95 men and 50 women, with a mean age 63.8±16.0 years. 79/145 (54.5%) patients received antibiotics, 52/145 (35%) had samples for culture and 49/145 (33.8%) were blood cultures. Pathogenic bacteria were isolated only in 7% of the patients. The patients with antibiotics had worse oxygenation, chest tomography and inflammatory markers, more admission to ICU, deaths, and prolonged hospital stay. Conclusion: Our results do not support the initial widespread use of antibiotics in hospitalized COVID-19 patients without knowing the pathogen and its susceptibility.
- Subjects
COVID-19; HOSPITAL patients; BACTERIAL cultures; PATHOGENIC bacteria; MIXED infections; INTENSIVE care units; HOSPITALS
- Publication
Archivos Venezolanos de Farmacología y Terapéutica, 2021, Vol 40, Issue 4, p424
- ISSN
0798-0264
- Publication type
Article
- DOI
10.5281/zenodo.5227632