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- Title
Atipia de células escamosas.
- Authors
Sofía Gómez-Macías, Gabriela
- Abstract
Squamous cell atypia (ASC) is referred to cytological changes suggestive of squamous intraepithelial lesion, but which are qualitatively and quantitatively insufficient to define it as such. They are divided into a dichotomous classification in atypia of cells of undetermined significance (ASC-US) and atypia of squamous cells it is not possible discard high-grade squamous intraepithelial lesion (ASC-H). 90% of ASC diagnoses correspond to ASC-US and the remaining 10% is reserved for diagnoses with the ASCH terminology. The histological correlation for the ASC-US category is more than 50% corresponds to benign conditions (59%), the low-grade lesion (32%), the high-grade lesion (3.8%) and only less than 1 % corresponded to a invasive carcinoma. Its relation with human papilloma virus of high oncogenic risk has been on average in 6-36%. In contrast to the ASC-H category, where the majority corresponded to high-grade intraepithelial lesions (53.3), followed by low-grade lesions (28.2%), benign conditions corresponded to 10.9%, and invasive carcinoma to 7.6%. Its relation with HPV of high oncogenic risk oscillates in different publications between 33.3%-83.6%. The management of both conditions is based on the guidelines of the American Society of Colposcopy and Cervical Pathology (ASCCP).
- Publication
Patologia Revista Latinoamericana, 2018, Vol 56, Issue 4, p238
- ISSN
0185-4305
- Publication type
Article