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- Title
Magnetic resonance fingerprinting for simultaneous renal T<sub>1</sub> and T2* mapping in a single breath‐hold.
- Authors
Hermann, Ingo; Chacon‐Caldera, Jorge; Brumer, Irène; Rieger, Benedikt; Weingärtner, Sebastian; Schad, Lothar R.; Zöllner, Frank G.
- Abstract
Purpose: To evaluate the use of magnetic resonance fingerprinting (MRF) for simultaneous quantification of T1 and T2∗ in a single breath‐hold in the kidneys. Methods: The proposed kidney MRF sequence was based on MRF echo‐planar imaging. Thirty‐five measurements per slice and overall 4 slices were measured in 15.4 seconds. Group matching was performed for in‐line quantification of T1 and T2∗. Images were acquired in a phantom and 8 healthy volunteers in coronal orientation. To evaluate our approach, region of interests were drawn in the kidneys to calculate mean values and standard deviations of the T1 and T2∗ times. Precision was calculated across multiple repeated MRF scans. Gaussian filtering is applied on baseline images to improve SNR and match stability. Results: T1 and T2∗ times acquired with MRF in the phantom showed good agreement with reference measurements and conventional mapping methods with deviations of less than 5% for T1 and less than 10% for T2∗. Baseline images in vivo were free of artifacts and relaxation times yielded good agreement with conventional methods and literature (deviation T1:7±4%, T2∗:6±3%). Conclusions: In this feasibility study, the proposed renal MRF sequence resulted in accurate T1 and T2∗ quantification in a single breath‐hold.
- Subjects
MAGNETIC resonance; ECHO-planar imaging; RESOURCE recovery facilities; STANDARD deviations
- Publication
Magnetic Resonance in Medicine, 2020, Vol 83, Issue 6, p1940
- ISSN
0740-3194
- Publication type
Article
- DOI
10.1002/mrm.28160