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- Title
Efficient Solvent-Free Synthesis of Indolizines Using CuBr Catalyst from Pyridine, Acetophenone, and Electron-Deficient Alkenes.
- Authors
Zhang, Xueguo; Zhang, Jianpeng; Liu, Zhengyi; Bi, Wenxuan; Shen, Jian; Li, Guang
- Abstract
Herein, we have developed a new approach for the synthesis of indolizine via Cu-catalyzed reaction of pyridine, acetophenone, and nitroolefin under mild conditions in high yields. This reaction involved the formation of C–N and C–C bonds and new indolizine compounds with high stereoselectivity and excellent functional group tolerance.
- Subjects
ACETOPHENONE; PYRIDINE; ALKENES; SUSTAINABLE chemistry; CATALYSTS; NITROALKENES
- Publication
Molecules, 2024, Vol 29, Issue 9, p2061
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules29092061