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- Title
Využití lokálních inhibitorů JAK v dermatologii.
- Authors
Matalová, Petra; Šimková, Karolína
- Abstract
The JAK/STAT signaling pathway is activated by a number of cytokines and growth factors. Drugs known as JAK inhibitors (JAKi) target cytokine signalization by either oral or topical administration. Topical application can minimize the risk of side effects observed with systemic application. The following article discusses different skin diseases in which local JAKi have positive therapeutic effect. Their use also reduces the risk of side effects of immunosuppressants and local corticosteroids.
- Subjects
ORAL drug administration; TOPICAL drug administration; GROWTH factors; SKIN diseases; TREATMENT effectiveness
- Publication
Dermatologie Pro Praxi, 2022, Vol 16, Issue 3, p164
- ISSN
1802-2960
- Publication type
Article
- DOI
10.36290/der.2022.033