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- Title
Antifungal activity of Ficus benghalensis and Vachellia nilotica against denture plaque Candida albicans-an invitro study.
- Authors
Srivastava, Krishanga; Philip, Jacob Mathew; Abraham, Helen Mary; Venkatakrishnan, C. J.
- Abstract
Background- Denture plaque Candida are opportunistic fungi that can cause various oral disease in certain conditions. The purpose of this study is to evaluate the antifungal effect of extracts of Ficus benghalensis and Vachellia nilotica against denture plaque Candida albicans to observe if their herbal extracts can potentially be used in the management of oral candidiasis. Materials and Methods- Antifungal activity was assessed using above mentioned plant extracts against strains of C. albicans isolated from 50 samples of denture plaque using 2 concentrations (5mg/ml and 10 mg/ml) in a liquid medium based anti-fungal assays. Results- The alcoholic and aqueous extracts of V.nilotica and the aqueous extract of F.benghalensis exhibited anti-candidal activity against 46 samples out of the 50 samples of C. albicans in both concentrations. Extracts prepared with other solvents did not demonstrate anticandidal activity. Conclusion- The alcoholic and aqueous extracts of V.nilotica and F.benghalensis have demonstrated anticandidal property and can be incorporated into various denture hygiene products to prevent candida associated denture stomatitis.
- Subjects
BANYAN tree; PLANT extracts; ANTIFUNGAL agents; CANDIDA albicans; DENTURES
- Publication
Journal of Positive School Psychology, 2022, Vol 6, Issue 3, p3966
- ISSN
2717-7564
- Publication type
Article