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- Title
AVATAR: Analysis for Visual Acuity Prediction After Eye Interventional Radiotherapy.
- Authors
PAGLIARA, MONICA MARIA; TAGLIAFERRI, LUCA; LENKOWICZ, JACOPO; AZARIO, LUIGI; GIATTINI, DARIO; FIONDA, BRUNO; SAMMARCO, MARIA GRAZIA; LANCELLOTTA, VALENTINA; GAMBACORTA, MARIA ANTONIETTA; BLASI, MARIA ANTONIETTA
- Abstract
Aim: The aim of this study was to detect clinical factors predictive of loss of visual acuity after treatment in order to develop a predictive model to help identify patients at risk of visual loss. Patients and Methods: This was a retrospective review of patients who underwent interventional radiotherapy (brachytherapy) with 106Ru plaque for primary uveal melanoma. A predictive nomogram for visual acuity loss at 3 years from treatment was developed. Results: A total of 152 patients were selected for the study. The actuarial probability of conservation of 20/40 vision or better was 0.74 at 1 year, 0.59 at 3 years, and 0.54 at 5 years after treatment. Factors positively correlated with loss of visual acuity included: age at start of treatment (p=0.004) and longitudinal basal diameter (p=0.057), while distance of the posterior margin of the tumor from the foveola was inversely correlated (p=0.0007). Conclusion: We identified risk factors affecting visual function and developed a predictive model and decision support tool (AVATAR nomogram).
- Subjects
VISUAL acuity; RADIOTHERAPY; PREDICTION models; RADIOISOTOPE brachytherapy; UVEAL diseases
- Publication
In Vivo, 2020, Vol 34, Issue 1, p381
- ISSN
0258-851X
- Publication type
Article
- DOI
10.21873/invivo.11784