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- Title
流 -固 -电多物理场耦合模型的红细胞流变学研究.
- Authors
胡晟; 王杨成; 吕晓永
- Abstract
The study of the mechanical deformation of red blood cell (RBC) suffered from fluid stress becomes more mature, but is insufficient for multi-physical fields, which involve the combination of electrical, acoustic, optical and thermal fields. Using COMSOL finite element software, a coupled model including three physical fluid-solid-electrics fields is built to study the migration simulation of two different RBC shapes with respect to spherocyte and normocyte. Compared to coupled model only involved in fluid-solid fields, the von Mises stress of spherocyte suffered from is greater than that of the normocyte when the electroosmotic flow generated by the electric field drives the cell migration. The effect of electroosmotic flow at 180μm/s leads to the RBC shape evolving into a “C” gesture. The spherocyte and normocyte have a different direction of rotation when they come across a pin obstacle due to the different shape. Regarding the coupled model with multi-physical fields presented, the motion trajectories of two cells reveal the possibility of separating different shaped cell relying on electroosmosis.
- Subjects
ERYTHROCYTES; ELECTRO-osmosis; ELECTROKINETICS; MICROFLUIDICS; RHEOLOGY
- Publication
Journal of Northeastern University (Natural Science), 2023, Vol 44, Issue 12, p1673
- ISSN
1005-3026
- Publication type
Article
- DOI
10.12068/j.issn.1005-3026.2023.12.001