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- Title
Silencing of lncRNA PVT1 ameliorates streptozotocin-induced pancreatic β cell injury and enhances insulin secretory capacity by regulating miR-181a-5p.
- Authors
Cheng, Yinqin; Hu, Qiaosheng; Zhou, Jie
- Abstract
The article reports on the study which examined the role of long noncoding ribonucleic acid (lncRNA) plasmacytoma variant translocation 1 (PVT1) in the development of diabetes mellitus (DM). The study was conducted in rat insulinoma (INS-1) cells damaged by streptozotocin (STZ). Other topics include cell apoptosis, oxidative stress, and luciferase reporter assay.
- Subjects
LINCRNA; NON-coding RNA
- Publication
Canadian Journal of Physiology & Pharmacology, 2021, Vol 99, Issue 3, p303
- ISSN
0008-4212
- Publication type
Article
- DOI
10.1139/cjpp-2020-0268