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- Title
Measurement of abdominal fat by CT compared to waist circumference and BMI in explaining the presence of coronary calcium.
- Authors
Snell-Bergeon, J. K; Hokanson, J. E; Kinney, G.L; Dabelea, D.; Ehrlich, J.; Eckel, R. H.; Ogden, L.; Rewers, M.
- Abstract
OBJECTIVE:: To evaluate the association between standard and computed tomography (CT)-based measures of obesity and subclinical atherosclerosis, defined as coronary artery calcium (CAC) by Electron Beam Computed Tomography (EBCT). DESIGN:: Cross-sectional, observational study of anthropometric and CT obesity measures and presence of CAC. SUBJECTS:: Participants were 383 men and 379 women, aged 20-58?y and asymptomatic for coronary artery disease (CAD). MEASUREMENTS:: Intra-abdominal fat (IAF) and subcutaneous fat (SQF) were measured at the level of lumbar 2-3 and 4-5 spaces, using EBCT. Body mass index (BMI) was calculated from height and weight, and minimum waist circumference and maximum hip circumference were measured. CAC was measured by EBCT. RESULTS:: In both men and women, BMI, waist circumference, IAF, and SQF were significantly related to CAC. However, BMI or waist circumference explained variation in the presence of CAC as well as IAF or SQF, univariately and after adjustment for additional cardiovascular risk factors. CONCLUSION:: CT-based obesity exposure measures are not superior to BMI or waist circumference in association studies of subclinical CAD.International Journal of Obesity (2004) 28, 1594-1599. doi:10.1038/sj.ijo.0802796 Published online 5 October 2004
- Subjects
TOMOGRAPHY; OBESITY; ATHEROSCLEROSIS; CORONARY arteries; ELECTRON beam curing; BODY weight
- Publication
International Journal of Obesity & Related Metabolic Disorders, 2004, Vol 28, Issue 12, p1594
- ISSN
0307-0565
- Publication type
Article
- DOI
10.1038/sj.ijo.0802796