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- Title
Eosinophilic esophagitis prevalence in an adult population undergoing upper endoscopy in southeastern Mexico.
- Authors
De la Cruz-Patiño, E.; Ruíz Juárez, I.; Meixueiro Daza, A.; Grube Pagola, P.; Roesch-Dietlen, F.; Remes-Troche, J. M.
- Abstract
Eosinophilic esophagitis ( Eo E) prevalence fluctuates according to the population studied and varies from 0.4% in an open population to 6.5% in subjects with esophageal symptoms. Even though this entity has been described in North American and European populations, it is still considered an 'unusual' condition in Latin America. The study aimed to determine Eo E prevalence in patients undergoing elective endoscopy in a tertiary referral center in southeastern Mexico. Consecutive patients were evaluated that had been referred to the Medical and Biological Research Institute, Veracruz, Mexico, for upper endoscopy due to gastrointestinal symptoms. Demographic variables and symptoms were analyzed in all the cases. Eight mucosal biopsies of the esophagus (four proximal and four distal) were obtained and were reviewed by a blinded pathologist. Histological diagnosis was established when the mean eosinophil count at a large magnification was ≥15. A total of 235 subjects (137 women, 51.16 years) were evaluated, and Eo E prevalence was 1.7% (4/235 95% confidence interval 0.2-3.6%). In all four cases, p H test were normal. Among patients with histological diagnosis of Eo E, a greater number of patients with a past history of asthma (50% vs. 19.3%, P = 0.04) and a tendency for a greater frequency of dysphagia (50% vs. 25%, P = 0.10). There were no differences in the endoscopic findings (rings, grooves, plaques, or stricture) when compared with the patients presenting with erosive esophagitis. Eo E prevalence among patients undergoing upper endoscopy from southeastern Mexico was 1.7%, which can be regarded as intermediate to low.
- Subjects
SOUTHEAST Mexico; EOSINOPHILIC esophagitis; ENDOSCOPIC gastrointestinal surgery; DISEASES in adults; SYMPTOMS; DISEASE prevalence; TERTIARY care; THERAPEUTICS
- Publication
Diseases of the Esophagus, 2015, Vol 28, Issue 6, p524
- ISSN
1120-8694
- Publication type
Article
- DOI
10.1111/dote.12238