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- Title
Successful treatment of urticarial vasculitis with omalizumab in children: a case series.
- Authors
Wang, Shan; Fu, Libing; Xiang, Xin; Zhang, Bin; Ma, Lin; Xing, Huan
- Abstract
Urticarial vasculitis (UV) is a small vessel leucocytoclastic vasculitis, which often needs to be distinguished from urticaria and other dermatoses. Treatment of UV in children is challenging because of the unsatisfying efficacy of antihistamines and the safety concern of long-term systemic corticosteroids or immunosuppressive agents. As a classic biological agent widely used in chronic spontaneous urticaria, omalizumab might also be a potential therapeutic option in the treatment of children with UV. This report presented four children, aged 4–6 years, with glucocorticoid-unresponsive UV successfully treated by omalizumab, thus providing evidence that omalizumab can be used to treat UV with good efficacy and tolerability in the paediatric population. This report presents four children, aged 4–6 years, with glucocorticoid-unresponsive urticarial vasculitis (UV) successfully treated by omalizumab, thus providing evidence that omalizumab is well tolerated and effective in treating UV in the paediatric population.
- Subjects
URTICARIA; OMALIZUMAB; TREATMENT effectiveness; CHILD patients; VASCULITIS; IMMUNOSUPPRESSIVE agents
- Publication
Clinical & Experimental Dermatology, 2023, Vol 48, Issue 10, p1145
- ISSN
0307-6938
- Publication type
Article
- DOI
10.1093/ced/llad192