OpenURL Connection Search

Select item for more details and to access through your institution.

Novel therapeutic approaches for heart failure by normalizing calcium cycling.
Published in:
Nature Reviews Drug Discovery, 2004, v. 3, n. 7, p. 1, doi. 10.1038/nrd1440
By:
- Wehrens, Xander H.T.;
- Marks, Andrew R.
Publication type:
Article
PKC inhibition ameliorates the cardiac phenotype in a mouse model of myotonic dystrophy type 1.
Published in:
2009
By:
- Guey-Shin Wang;
- Kuyumcu-Martinez, Muge N.;
- Sarma, Satyam;
- Mathur, Nitin;
- Wehrens, Xander H.T.;
- Cooper, Thomas A.;
- Wang, Guey-Shin
Publication type:
journal article
Cardiac‐specific ablation of glutaredoxin 3 leads to cardiac hypertrophy and heart failure.
Published in:
Physiological Reports, 2019, v. 7, n. 8, p. N.PAG, doi. 10.14814/phy2.14071
By:
- Donelson, Jimmonique;
- Wang, Qiongling;
- Monroe, Tanner O.;
- Jiang, Xiqian;
- Zhou, Jianjie;
- Yu, Han;
- Mo, Qianxing;
- Sun, Qin;
- Marini, Juan C.;
- Wang, Xinquan;
- Nakata, Paul A.;
- Hirschi, Kendal D.;
- Wang, Jin;
- Rodney, George G.;
- Wehrens, Xander H.T.;
- Cheng, Ninghui
Publication type:
Article
Ranolazine prevents pressure overload‐induced cardiac hypertrophy and heart failure by restoring aberrant Na+ and Ca2+ handling.
Published in:
Journal of Cellular Physiology, 2019, v. 234, n. 7, p. 11587, doi. 10.1002/jcp.27791
By:
- Nie, Jiali;
- Duan, Quanlu;
- He, Mengying;
- Li, Xianqing;
- Wang, Bei;
- Zhou, Chi;
- Wu, Lujin;
- Wen, Zheng;
- Chen, Chen;
- Wang, Dao Wu;
- Alsina, Katherina M.;
- Wehrens, Xander H.T.;
- Wang, Dao Wen;
- Ni, Li
Publication type:
Article
Ryanodine Receptor-Targeted Anti-Arrhythmic Therapy.
Published in:
Annals of the New York Academy of Sciences, 2005, v. 1047, n. 1, p. 366, doi. 10.1196/annals.1341.032
By:
- WEHRENS, XANDER H.T.;
- LEHNART, STEPHAN E.;
- MARKS, ANDREW R.
Publication type:
Article
Emerging roles of junctophilin-2 in the heart and implications for cardiac diseases.
Published in:
Cardiovascular Research, 2014, v. 103, n. 2, p. 198, doi. 10.1093/cvr/cvu151
By:
- Beavers, David L.;
- Landstrom, Andrew P.;
- Chiang, David Y.;
- Wehrens, Xander H.T.
Publication type:
Article
Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation.
Published in:
Cardiovascular Research, 2014, v. 103, n. 1, p. 178, doi. 10.1093/cvr/cvu123
By:
- Chiang, David Y.;
- Li, Na;
- Wang, Qiongling;
- Alsina, Katherina M.;
- Quick, Ann P.;
- Reynolds, Julia O.;
- Wang, Guoliang;
- Skapura, Darlene;
- Voigt, Niels;
- Dobrev, Dobromir;
- Wehrens, Xander H.T.
Publication type:
Article
Ryanodine receptor phosphorylation by oxidized CaMKII contributes to the cardiotoxic effects of cardiac glycosides.
Published in:
Cardiovascular Research, 2014, v. 101, n. 1, p. 165, doi. 10.1093/cvr/cvt233
By:
- Ho, Hsiang-Ting;
- Liu, Bin;
- Snyder, Jedidiah S.;
- Lou, Qing;
- Brundage, Elizabeth A.;
- Velez-Cortes, Florencia;
- Wang, Honglan;
- Ziolo, Mark T.;
- Anderson, Mark E.;
- Sen, Chandan K.;
- Wehrens, Xander H.T.;
- Fedorov, Vadim V.;
- Biesiadecki, Brandon J.;
- Hund, Thomas J.;
- Györke, Sándor
Publication type:
Article
Critical roles of junctophilin-2 in T-tubule and excitation–contraction coupling maturation during postnatal development.
Published in:
Cardiovascular Research, 2013, v. 100, n. 1, p. 54, doi. 10.1093/cvr/cvt180
By:
- Chen, Biyi;
- Guo, Ang;
- Zhang, Caimei;
- Chen, Rong;
- Zhu, Yanqi;
- Hong, Jiang;
- Kutschke, William;
- Zimmerman, Kathy;
- Weiss, Robert M.;
- Zingman, Leonid;
- Anderson, Mark E.;
- Wehrens, Xander H.T.;
- Song, Long-Sheng
Publication type:
Article
Junctophilin-2 is necessary for T-tubule maturation during mouse heart development.
Published in:
Cardiovascular Research, 2013, v. 100, n. 1, p. 44, doi. 10.1093/cvr/cvt133
By:
- Reynolds, Julia O.;
- Chiang, David Y.;
- Wang, Wei;
- Beavers, David L.;
- Dixit, Sayali S.;
- Skapura, Darlene G.;
- Landstrom, Andrew P.;
- Song, Long-Sheng;
- Ackerman, Michael J.;
- Wehrens, Xander H.T.
Publication type:
Article
The ryanodine receptor channel as a molecular motif in atrial fibrillation: pathophysiological and therapeutic implications.
Published in:
Cardiovascular Research, 2011, v. 89, n. 4, p. 734, doi. 10.1093/cvr/cvq324
By:
- Dobrev, Dobromir;
- Voigt, Niels;
- Wehrens, Xander H.T.
Publication type:
Article
Angiogenesis-independent cardioprotection in FGF-1 transgenic mice.
Published in:
Cardiovascular Research, 2002, v. 55, n. 4, p. 768, doi. 10.1016/S0008-6363(02)00494-7
By:
- Buehler, Alexandra;
- Martire, Alessandra;
- Strohm, Claudia;
- Wolfram, Swen;
- Fernandez, Borja;
- Palmen, Meindert;
- Wehrens, Xander H.T;
- Doevendans, Pieter A;
- Franz, Wolfgang M;
- Schaper, Wolfgang;
- Zimmermann, René
Publication type:
Article
Mouse electrocardiography.
Published in:
Cardiovascular Research, 2000, v. 45, n. 1, p. 231
By:
- Wehrens, Xander H.T.;
- Kirchhoff, Susanne;
- Doevendans, Pieter A.
Publication type:
Article
Novel Insights in the Congenital Long QT Syndrome.
Published in:
Annals of Internal Medicine, 2002, v. 137, n. 12, p. 981, doi. 10.7326/0003-4819-137-12-200212170-00012
By:
- Wehrens, Xander H.T.;
- Vos, Marc A.;
- Doevendans, Pieter A.;
- Wellens, Hein J.J.
Publication type:
Article
The mitochondrial uniporter controls fight or flight heart rate increases.
Published in:
Nature Communications, 2015, v. 6, n. 1, p. 6081, doi. 10.1038/ncomms7081
By:
- Wu, Yuejin;
- Rasmussen, Tyler P.;
- Koval, Olha M;
- Joiner, Mei-ling A.;
- Hall, Duane D.;
- Chen, Biyi;
- Luczak, Elizabeth D.;
- Wang, Qiongling;
- Rokita, Adam G.;
- Wehrens, Xander H.T.;
- Song, Long-Sheng;
- Anderson, Mark E.
Publication type:
Article
Ca2+/calmodulin‐dependent kinase IIδC‐induced chronic heart failure does not depend on sarcoplasmic reticulum Ca2+ leak.
Published in:
ESC Heart Failure, 2024, v. 11, n. 4, p. 2191, doi. 10.1002/ehf2.14772
By:
- Dewenter, Matthias;
- Seitz, Tilmann;
- Steinbrecher, Julia H.;
- Westenbrink, B. Daan;
- Ling, Haiyun;
- Lehnart, Stephan E.;
- Wehrens, Xander H.T.;
- Backs, Johannes;
- Brown, Joan Heller;
- Maier, Lars S.;
- Neef, Stefan
Publication type:
Article
Methyl-CpG binding-protein 2 function in cholinergic neurons mediates cardiac arrhythmogenesis.
Published in:
Human Molecular Genetics, 2016, v. 25, n. 22, p. 4983, doi. 10.1093/hmg/ddw326
By:
- Herrera, José A.;
- Ward, Christopher S.;
- Wehrens, Xander H.T.;
- Neul, Jeffrey L.
Publication type:
Article
In Vivo Cardiac Electrophysiology in Mice: Determination of Atrial and Ventricular Arrhythmic Substrates.
Published in:
Current Protocols, 2024, v. 4, n. 2, p. 1, doi. 10.1002/cpz1.994
By:
- Navarro‐Garcia, Jose Alberto;
- Bruns, Florian;
- Moore, Oliver M.;
- Tekook, Marcel A.;
- Dobrev, Dobromir;
- Miyake, Christina Y.;
- Wehrens, Xander H.T.
Publication type:
Article
Heart-specific overexpression of CUGBP1 reproduces functional and molecular abnormalities of myotonic dystrophy type 1.
Published in:
Human Molecular Genetics, 2010, v. 19, n. 6, p. 1066, doi. 10.1093/hmg/ddp570
By:
- Koshelev, Misha;
- Sarma, Satyam;
- Price, Roger E.;
- Wehrens, Xander H.T.;
- Cooper, Thomas A.
Publication type:
Article
A Novel mutation L619F in the cardiac Na+ channel SCN5A associated with long-QT syndrome (LQT3): a role for the I-II linker in inactivation gating (Communicated by Mark H. Paalman) Online Citation: Human Mutation, Mutation in Brief #607(2002) online http://www.interscience.wiley.com/humanmutation/pdf/mutation/607.pdf)
Published in:
Human Mutation, 2003, v. 21, n. 5, p. 552, doi. 10.1002/humu.9136
By:
- Xander H.T. Wehrens;
- Tom Rossenbacker;
- Roselie J. Jongbloed;
- Marc Gewillig;
- Hein Heidbüchel;
- Pieter A. Doevendans;
- Marc A. Vos;
- Hein J.J. Wellens;
- Robert S. Kass
Publication type:
Article
A Novel mutation L619F in the cardiac Na+ channel SCN5A associated with long‐QT syndrome (LQT3): a role for the I‐II linker in inactivation gatingCommunicated by Mark H. PaalmanOnline Citation: Human Mutation, Mutation in Brief #607(2002) onlinehttp://www.interscience.wiley.com/humanmutation/pdf/mutation/607.pdf
Published in:
Human Mutation, 2003, v. 21, n. 5, p. 552, doi. 10.1002/humu.9136
By:
- Xander H.T. Wehrens;
- Tom Rossenbacker;
- Roselie J. Jongbloed;
- Marc Gewillig;
- Hein Heidbüchel;
- Pieter A. Doevendans;
- Marc A. Vos;
- Hein J.J. Wellens;
- Robert S. Kass
Publication type:
Article

Found: 21

Novel therapeutic approaches for heart failure by normalizing calcium cycling.

PKC inhibition ameliorates the cardiac phenotype in a mouse model of myotonic dystrophy type 1.

Cardiac‐specific ablation of glutaredoxin 3 leads to cardiac hypertrophy and heart failure.

Ranolazine prevents pressure overload‐induced cardiac hypertrophy and heart failure by restoring aberrant Na<sup>+</sup> and Ca<sup>2+</sup> handling.

Ryanodine Receptor-Targeted Anti-Arrhythmic Therapy.

Emerging roles of junctophilin-2 in the heart and implications for cardiac diseases.

Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation.

Ryanodine receptor phosphorylation by oxidized CaMKII contributes to the cardiotoxic effects of cardiac glycosides.

Critical roles of junctophilin-2 in T-tubule and excitation–contraction coupling maturation during postnatal development.

Junctophilin-2 is necessary for T-tubule maturation during mouse heart development.

The ryanodine receptor channel as a molecular motif in atrial fibrillation: pathophysiological and therapeutic implications.

Angiogenesis-independent cardioprotection in FGF-1 transgenic mice.

Mouse electrocardiography.

Novel Insights in the Congenital Long QT Syndrome.

The mitochondrial uniporter controls fight or flight heart rate increases.

Ca2+/calmodulin‐dependent kinase IIδC‐induced chronic heart failure does not depend on sarcoplasmic reticulum Ca2+ leak.

Methyl-CpG binding-protein 2 function in cholinergic neurons mediates cardiac arrhythmogenesis.

In Vivo Cardiac Electrophysiology in Mice: Determination of Atrial and Ventricular Arrhythmic Substrates.

Heart-specific overexpression of CUGBP1 reproduces functional and molecular abnormalities of myotonic dystrophy type 1.