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- Title
Acquired von Willebrand's Syndrome Causing a Hemorrhagic Diathesis in a Patient with Hypothyroidism.
- Authors
ATTIVISSIMO, LORI ANN; LICHTMAN, STUART M.; KLEIN, IRWIN
- Abstract
The occurrence of bleeding diathesis with menorrhagia and easy bruising may occur in patients with moderate to severe hypothyroidism sometimes linked to acquired von Willebrand's disease (VWD). We describe a patient with profound hypothyroidism in whom the diagnosis of hypothyroidism was established while evaluating uncontrolled gingival bleeding after a dental procedure. Thyroid hormone replacement led to a rise in von Willebrand factor, factor VIIIC, and a significant fall in the elevated bleeding time from 15 to 8 min. Acquired von Willebrand's disease is an unusual manifestation of hypothyroidism and is reversible.
- Publication
Thyroid, 1995, Vol 5, Issue 5, p399
- ISSN
1050-7256
- Publication type
Article
- DOI
10.1089/thy.1995.5.399