We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Host Protective Immune Responses against Influenza A Virus Infection.
- Authors
Jung, Hi Eun; Lee, Heung Kyu
- Abstract
Influenza viruses cause infectious respiratory disease characterized by fever, myalgia, and congestion, ranging in severity from mild to life-threating. Although enormous efforts have aimed to prevent and treat influenza infections, seasonal and pandemic influenza outbreaks remain a major public health concern. This is largely because influenza viruses rapidly undergo genetic mutations that restrict the long-lasting efficacy of vaccine-induced immune responses and therapeutic regimens. In this review, we discuss the virological features of influenza A viruses and provide an overview of current knowledge of the innate sensing of invading influenza viruses and the protective immune responses in the host.
- Subjects
VIRUS diseases; INFLUENZA A virus; PANDEMICS; IMMUNE response; RESPIRATORY diseases; SEASONAL influenza
- Publication
Viruses (1999-4915), 2020, Vol 12, Issue 5, p504
- ISSN
1999-4915
- Publication type
Article
- DOI
10.3390/v12050504