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- Title
Effects of Rhizoclonium hieroglyphicum and Spirogyra neglecta combined freshwater algal extract on blood glucose, lipids and oxidative markers in diabetic rats.
- Authors
Janthip, Rattanaporn; Lailerd, Narissara; Wangchareon, Wiwat; Mengumphan, Kriangsak; Amornlerdpison, Doungporn
- Abstract
Rhizoclonium hieroglyphicum and Spirogyra neglecta are freshwater green macroalgae that exhibit antioxidant, anti-inflammatory and anti-diabetic properties. R. hieroglyphicum extract (RE) and S. neglecta extract (SE) were mixed to obtain a combined algal extract (RSE), and RSE was used as functional ingredient in an algal product (RSP). The total phenolic content of RE and SE was 8.58 and 107.02 mgGAE/g extract respectively. RSE and/or RSP, respectively, decreased glucose level by 38.53% and 41.28%, triglycerides by 2.96% and 36.84%, total cholesterol by 25.98% and 21.07% and malondialdehyde by 32.45% and 28.46% in diabetic rats but significantly increased superoxide dismutase, catalase and glutathione peroxidase activities. These findings indicate that RSE and RSP possess antihyperglycemic, anti-hypercholesterolemic and antioxidative stress effects.
- Subjects
BLOOD sugar; LIPIDS; FRESH water; SUPEROXIDE dismutase; EXTRACTS; GLUTATHIONE peroxidase
- Publication
Maejo International Journal of Science & Technology, 2020, Vol 14, Issue 2, p184
- ISSN
1905-7873
- Publication type
Article