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- Title
The New Alkaloids from Antidesma cuspidatum M.A.
- Authors
Elya, Berna; Forestrania, Roshamur C.; Ropi, Mat; Kosela, Soleh; Awang, Khalijah; Omar, Hanita; Hadi, A. Hamid A.
- Abstract
Two new alkaloids, cuspidatin (1) and cuspidatinol (2), were isolated from Antidesma cuspidatum M.A. (Euphorbiaceae). The structures were determined by means of spectroscopic analysis (IR, MS, and NMR spectroscopy). The results of cytotoxicity evaluation showed that compounds 1 and 2 were inhibitory to L1210 cells, with IC50 values 8.41 and 6.36 µg/mL respectively.
- Subjects
ALKALOIDS; ANTIDESMA; NUCLEAR magnetic resonance; INFRARED radiation; CELL-mediated cytotoxicity; EUPHORBIACEAE
- Publication
Records of Natural Products, 2014, Vol 8, Issue 4, p342
- ISSN
1307-6167
- Publication type
Article