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- Title
J wave dynamicity during coronary angiography and intracoronary acetylcholine administration.
- Authors
Aizawa, Yoshiyasu; Ohashi, Narutaka; Kawamura, Akio; Ogawa, Satoshi; Aizawa, Yoshifusa
- Abstract
Background: J‐waves may be observed during coronary angiography (CAG) or intracoronary acetylcholine (ACh) administration, but their significance is unknown. Methods: Forty‐nine patients, 59.1 ± 11.5 years old and 59% male, were studied on suspicion of vasospastic angina, and J wave dynamicity was compared between CAG and Ach administration. Results: Diagnostic (≥0.1 mV) or nondiagnostic (<0.1 mV) J waves in 9 and 3 patients, respectively, were augmented, and J waves were newly observed in 2 patients during CAG and Ach administration. Similar changes in the J‐wave amplitude were observed: from 0.10 ± 0.09 mV to 0.20 ± 0.15 mV (p <.002) and from 0.10 ± 0.10 mV to 0.20 ± 0.16 mV (p <.001) during CAG and Ach administration, respectively. J waves were located in the inferior leads and changed only during the right coronary interventions. In the remaining 35 patients, J waves were absent before and during the coronary interventions. Augmentation of J waves was found when the RR interval was shortened in some patients. Injection of anoxic media into the coronary artery might induce a conduction delay from myocardial ischemia that manifests as augmentation or new occurrence of J waves. Conclusions: Both CAG and intracoronary Ach administration affected J waves similarly in the same individuals. A myocardial ischemia‐induced conduction delay may be responsible for the changes in J waves, but further studies are needed.
- Subjects
CORONARY arterial radiography; CORONARY vasospasm; MYOCARDIAL ischemia; CORONARY angiography; ACETYLCHOLINE; COMPARATIVE studies; CORONARY artery disease; ARRHYTHMIA; DISEASE complications
- Publication
Pacing & Clinical Electrophysiology, 2023, Vol 46, Issue 8, p868
- ISSN
0147-8389
- Publication type
Article
- DOI
10.1111/pace.14787