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- Title
Systems biology from a yeast omics perspective
- Authors
Snyder, Michael; Gallagher, Jennifer E.G.
- Abstract
Abstract: Systems biology represents a paradigm shift from the study of individual genes, proteins or other components to that of the analysis of entire pathways, cellular, developmental, or organismal processes. Large scale studies, primarily initiated in Saccharomyces cerevisiae, have allowed the identification and characterization of components on an unprecedented level. Large scale interaction, transcription factor binding and phosphorylation data have enabled the elucidation of global regulatory networks. These studies have helped provide an understanding of cellular pathways and processes at a global and systems level.
- Subjects
SYSTEMS biology; YEAST; YEAST fungi genetics; FUNGAL proteins; SACCHAROMYCES cerevisiae; TRANSCRIPTION factors; PHOSPHORYLATION; CELLULAR signal transduction
- Publication
FEBS Letters, 2009, Vol 583, Issue 24, p3895
- ISSN
0014-5793
- Publication type
Article
- DOI
10.1016/j.febslet.2009.11.011