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The Aggregation-Prone Intracellular Serpin SRP-2 Fails to Transit the ER in Caenorhabditis elegans.
Published in:
Genetics, 2015, v. 200, n. 1, p. 207, doi. 10.1534/genetics.115.176180
By:
- Silverman, Richard M.;
- Cummings, Erin E.;
- O'Reilly, Linda P.;
- Miedel, Mark T.;
- Silverman, Gary A.;
- Luke, Cliff J.;
- Perlmutter, David H.;
- Pak, Stephen C.
Publication type:
Article
Functional Genomics of ABCA3 Variants.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2020, v. 63, n. 4, p. 436, doi. 10.1165/rcmb.2020-0034MA
By:
- Wambach, Jennifer A.;
- Ping Yang;
- Wegner, Daniel J.;
- Heins, Hillary B.;
- Luke, Cliff;
- Fuhai Li;
- White, Frances V.;
- Cole, F. Sessions
Publication type:
Article
Functional characterization of four ATP‐binding cassette transporter A3 gene (ABCA3) variants.
Published in:
Human Mutation, 2020, v. 41, n. 7, p. 1298, doi. 10.1002/humu.24014
By:
- Hu, June Y.;
- Yang, Ping;
- Wegner, Daniel J.;
- Heins, Hillary B.;
- Luke, Cliff J.;
- Li, Fuhai;
- White, Frances V.;
- Silverman, Gary A.;
- Sessions Cole, F.;
- Wambach, Jennifer A.
Publication type:
Article
Serum squamous cell carcinoma antigen as an early indicator of response during therapy of cervical cancer.
Published in:
British Journal of Cancer, 2018, v. 118, n. 1, p. 72, doi. 10.1038/bjc.2017.390
By:
- Markovina, Stephanie;
- Wang, Songyan;
- Henke, Lauren E;
- Luke, Cliff J;
- Pak, Stephen C;
- DeWees, Todd;
- Pfeifer, John D;
- Schwarz, Julie K;
- Liu, Weijun;
- Chen, Shuai;
- Mutch, David;
- Wang, Xiaowei;
- Powell, Matthew A;
- Siegel, Barry A;
- Dehdashti, Farrokh;
- Silverman, Gary A;
- Grigsby, Perry W
Publication type:
Article
Serum squamous cell carcinoma antigen as an early indicator of response during therapy of cervical cancer.
Published in:
2017
By:
- Markovina, Stephanie;
- Wang, Songyan;
- Henke, Lauren E;
- Luke, Cliff J;
- Pak, Stephen C;
- DeWees, Todd;
- Pfeifer, John D;
- Schwarz, Julie K;
- Liu, Weijun;
- Chen, Shuai;
- Mutch, David;
- Wang, Xiaowei;
- Powell, Matthew A;
- Siegel, Barry A;
- Dehdashti, Farrokh;
- Silverman, Gary A;
- Grigsby, Perry W
Publication type:
journal article
CemOrange2 fusions facilitate multifluorophore subcellular imaging in C. elegans.
Published in:
PLoS ONE, 2019, v. 14, n. 3, p. 1, doi. 10.1371/journal.pone.0214257
By:
- Thomas, Brian J.;
- Wight, Ira E.;
- Chou, Wendy Y. Y.;
- Moreno, Marco;
- Dawson, Zachary;
- Homayouni, Arielle;
- Huang, Huiyan;
- Kim, Hyori;
- Jia, Hanna;
- Buland, Justin R.;
- Wambach, Jennifer A.;
- Cole, F. Sessions;
- Pak, Stephen C.;
- Silverman, Gary A.;
- Luke, Cliff J.
Publication type:
Article
A genome-wide RNAi screen identifies potential drug targets in a C. elegans model of α1-antitrypsin deficiency.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 19, p. 5123, doi. 10.1093/hmg/ddu236
By:
- O'Reilly, Linda P.;
- Long, Olivia S.;
- Cobanoglu, Murat C.;
- Benson, Joshua A.;
- Luke, Cliff J.;
- Miedel, Mark T.;
- Hale, Pamela;
- Perlmutter, David H.;
- Bahar, Ivet;
- Silverman, Gary A.;
- Pak, Stephen C.
Publication type:
Article
A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnover.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 19, p. 5109, doi. 10.1093/hmg/ddu235
By:
- Long, Olivia S.;
- Benson, Joshua A.;
- Kwak, Joon Hyeok;
- Luke, Cliff J.;
- Gosai, Sager J.;
- O'Reilly, Linda P.;
- Wang, Yan;
- Li, Jie;
- Vetica, Anne C.;
- Miedel, Mark T.;
- Stolz, Donna B.;
- Watkins, Simon C.;
- Züchner, Stephan;
- Perlmutter, David H.;
- Silverman, Gary A.;
- Pak, Stephen C.
Publication type:
Article
Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells.
Published in:
International Journal of Cancer, 2000, v. 89, n. 4, p. 368, doi. 10.1002/1097-0215(20000720)89:4<368::AID-IJC9>3.0.CO;2-6
By:
- Uemura, Yoshiki;
- Pak, Stephen C.;
- Luke, Cliff;
- Çataltepe, Sule;
- Tsu, Christopher;
- Schick, Charles;
- Kamachi, Yoshiro;
- Pomeroy, Scott L.;
- Perlmutter, David H.;
- Silverman, Gary A.
Publication type:
Article
A Small Conductance Calcium-Activated K<sup>+</sup> Channel in <i>C. elegans</i>, KCNL-2, Plays a Role in the Regulation of the Rate of Egg-Laying.
Published in:
PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0075869
By:
- Chotoo, Cavita K.;
- Silverman, Gary A.;
- Devor, Daniel C.;
- Luke, Cliff J.
Publication type:
Article
A Pro-Cathepsin L Mutant Is a Luminal Substrate for Endoplasmic-Reticulum-Associated Degradation in C. elegans.
Published in:
PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0040145
By:
- Miedel, Mark T.;
- Graf, Nathan J.;
- Stephen, Kate E.;
- Long, Olivia S.;
- Pak, Stephen C.;
- Perlmutter, David H.;
- Silverman, Gary A.;
- Luke, Cliff J.
Publication type:
Article
Automated High-Content Live Animal Drug Screening Using C. elegans Expressing the Aggregation Prone Serpin α1-antitrypsin Z.
Published in:
PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0015460
By:
- Gosai, Sager J.;
- Joon Hyeok Kwak;
- Luke, Cliff J.;
- Long, Olivia S.;
- King, Dale E.;
- Kovatch, Kevin J.;
- Johnston, Paul A.;
- Tong Ying Shun;
- Lazo, John S.;
- Perlmutter, David H.;
- Silverman, Gary A.;
- Pak, Stephen C.
Publication type:
Article
SERPINB3 (SCCA1) inhibits cathepsin L and lysoptosis, protecting cervical cancer cells from chemoradiation.
Published in:
Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-021-02893-6
By:
- Wang, Songyan;
- Luke, Cliff J.;
- Pak, Stephen C.;
- Shi, Victoria;
- Chen, Liyun;
- Moore, Jonathan;
- Andress, Arlise P.;
- Jayachandran, Kay;
- Zhang, Jin;
- Huang, Yi;
- Platik, Marina;
- Apicelli, Anthony A.;
- Schwarz, Julie K.;
- Grigsby, Perry W.;
- Silverman, Gary A.;
- Markovina, Stephanie
Publication type:
Article
Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins.
Published in:
Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-021-02953-x
By:
- Luke, Cliff J.;
- Markovina, Stephanie;
- Good, Misty;
- Wight, Ira E.;
- Thomas, Brian J.;
- Linneman, John M.;
- Lanik, Wyatt E.;
- Koroleva, Olga;
- Coffman, Maggie R.;
- Miedel, Mark T.;
- Gong, Qingqing;
- Andress, Arlise;
- Campos Guerrero, Marlene;
- Wang, Songyan;
- Chen, LiYun;
- Beatty, Wandy L.;
- Hausmann, Kelsey N.;
- White, Frances V.;
- Fitzpatrick, James A. J.;
- Orvedahl, Anthony
Publication type:
Article
Human SERPINB12 Is an Abundant Intracellular Serpin Expressed in Most Surface and Glandular Epithelia.
Published in:
Journal of Histochemistry & Cytochemistry, 2015, v. 63, n. 11, p. 854, doi. 10.1369/0022155415600498
By:
- Niehaus, Jason Z.;
- Good, Misty;
- Jackson, Laura E.;
- Ozolek, John A.;
- Silverman, Gary A.;
- Luke, Cliff J.
Publication type:
Article
Necrotic cell death: harnessing the Dark side of the Force in mammary gland involution.
Published in:
Nature Cell Biology, 2011, v. 13, n. 3, p. 197, doi. 10.1038/ncb0311-197
By:
- Luke, Cliff J.;
- Silverman, Gary A.
Publication type:
Article
Triage implementation in resource-limited emergency departments: sharing tools and experience from the Pacific region.
Published in:
International Journal of Emergency Medicine, 2024, v. 17, n. 1, p. 1, doi. 10.1186/s12245-024-00583-8
By:
- Mitchell, Rob;
- White, Libby;
- Elton, Leigh;
- Luke, Cliff;
- Bornstein, Sarah;
- Atua, Vincent
Publication type:
Article
Patient-derived small intestinal myofibroblasts direct perfused, physiologically responsive capillary development in a microfluidic Gut-on-a-Chip Model.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-60672-5
By:
- Seiler, Kristen M.;
- Bajinting, Adam;
- Alvarado, David M.;
- Traore, Mahama A.;
- Binkley, Michael M.;
- Goo, William H.;
- Lanik, Wyatt E.;
- Ou, Jocelyn;
- Ismail, Usama;
- Iticovici, Micah;
- King, Cristi R.;
- VanDussen, Kelli L.;
- Swietlicki, Elzbieta A.;
- Gazit, Vered;
- Guo, Jun;
- Luke, Cliff J.;
- Stappenbeck, Thaddeus;
- Ciorba, Matthew A.;
- George, Steven C.;
- Meacham, J. Mark
Publication type:
Article
Deficient and Null Variants of SERPINA1 Are Proteotoxic in a Caenorhabditis elegans Model of α1-Antitrypsin Deficiency.
Published in:
PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0141542
By:
- Cummings, Erin E.;
- O’Reilly, Linda P.;
- King, Dale E.;
- Silverman, Richard M.;
- Miedel, Mark T.;
- Luke, Cliff J.;
- Perlmutter, David H.;
- Silverman, Gary A.;
- Pak, Stephen C.
Publication type:
Article

Found: 19