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- Title
Seroprevalence of malaria in blood donors and multi-transfused patients in Northern India: Relevance to prevention of transfusiontransmissible malaria.
- Authors
Dubey, Anju; Elhence, Priti; Ghoshal, Ujjala; Verma, Anupam
- Abstract
Background: Transfusion-transmissible malaria (TTM) is a major concern in malaria endemic countries. A study was therefore conducted to know sero-prevalence of malaria in blood donors and the risk of TTM to multi-transfused patients at our hospital. Materials and Methods: Study subjects were: eligible blood donors (n = 1000), donors deferred due to history of fever in the last 3 months (n = 100), and multi-transfused patients (n = 200). Screening for malaria was done by slide microscopy, immunochromatographic rapid diagnostic test (RDT) for malaria antigen, and anti-malaria antibody by enzyme linked immunosorbent assay. Results: Malaria antibody prevalence in eligible donors and donors with history of fever, thalassemia patients, and in other multi-transfused patients was 16.9%, 22%, 6%, and 15%, respectively. None of the donors were positive for malaria on microscopic examination. None of the blood donors except one donor with history of fever, tested positive with RDT. Conclusion: Malaria antibody prevalence in blood donors at our center is high. As blood units donated by such donors have high-risk potential, special processing may be undertaken to reduce the risk of TTM.
- Subjects
INDIA; RISK of malaria; ACADEMIC medical centers; BLOOD transfusion; BLOOD donors; CHI-squared test; ENZYME-linked immunosorbent assay; IMMUNOGLOBULINS; T-test (Statistics); PILOT projects; EQUIPMENT &; supplies; DISEASE prevalence; RETROSPECTIVE studies; DATA analysis software; DESCRIPTIVE statistics
- Publication
Asian Journal of Transfusion Science, 2012, Vol 6, Issue 2, p174
- ISSN
0973-6247
- Publication type
Article
- DOI
10.4103/0973-6247.98937