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- Title
Synthesis, UV/Vis and Fluorescence studies of Naphthoquinone Pyridyl Tetrazole-based Chemical Probe.
- Authors
BALAKRISHNA, K.; VIJAYA LAKSHMI, D.; MUSTAFA, S.; REDDY, K. S.; GHORPADE, T. K.
- Abstract
2-(dimethylamino)-3-(5-(pyridin-2-yl)-1H-tetrazol-1-yl)naphthalene-1,4-dione (2) has been synthesized. The UV/Vis studies of 2-(dimethylamino)-3-(5-(pyridin-2-yl)-1H-tetrazol-1-yl)naphthalene-1,4-dione (2) with different metal ions were performed in aqueous dimethylformamide and were correlated with fluorescence studies of the same. The compound showed higher selectivity and sensitivity for Zn2+ ions. Thus this compound could be utilized as a turn-on probe for fluorescent imaging of Zn2+ ions in living cells.
- Subjects
NAPHTHOQUINONE; TETRAZOLES; NAPHTHALENE synthesis; DIMETHYLFORMAMIDE; FLUORESCENCE
- Publication
Indian Journal of Pharmaceutical Sciences, 2018, Vol 80, Issue 4, p772
- ISSN
0250-474X
- Publication type
Article
- DOI
10.4172/pharmaceutical-sciences.1000420