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- Title
EDAD Y PERFIL CLÍNICO DE LOS PACIENTES HOSPITALIZADOS POR MONONUCLEOSIS INFECCIOSA.
- Authors
González Quijada, Santiago; Cuesta, Marta; Valledor, Ana Riego; Gil, Ana; Pérez Tárrego, Cristina
- Abstract
Background: It is unclear whether age may influence the clinical expression of Infectious mononucleosis (IM), and therefore constitute a risk factor for hospitalization. The aim of the study was to verify the clinical profile of patients hospitalized for this cause varies substantially with age. Patients and methods: This is a retrospective case-control study, based on the collection of secondary data from 217 cases of IM admitted to a referral hospital between 1995-2008. We performed a comparative analysis of clinical profile by age. Results: The frequency of patients by age groups were <10 years (40 cases, 18.4%), 10-24 (154, 70.9%), and > 24 (23, 10.5%). The age range was from 0.2 to 78 years with a mean of 5 ± 2 years, 17 ± 4 and 33 ± 11 years, respectively. A typical or usual clinical profile (pharyngitis, fever and lymphadenopathy), was more common in children and adolescents than in adults: 77%, 76%, and 34.6% respectively (p <0.001). The presence of relative lymphocytosis was not superior to 60% in any of the three groups. Anemia was found in 49% of children compared to 11% of adolescents; P <0.001. The AST (> 10 times normal), and total bilirubin in the blood were elevated more frequently in adults than in adolescents: 13.6% vs. 4.9%, P <0.05, and 41, 1% vs. 24.6%, P <0.01, respectively. Conclusions: Children and adults hospitalized with MI have an atypical clinical or analytical profile more often than adolescents in the same situation. This data, along with the severity of the disease, has been promoting the hospitalization.
- Subjects
HOSPITAL patients; MONONUCLEOSIS; SECONDARY analysis; PHARYNGITIS; LYMPHOCYTOSIS; BILIRUBIN; DISEASE risk factors
- Publication
Electronic Journal of Biomedicine, 2012, Issue 3, p1
- ISSN
1697-090X
- Publication type
Article