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- Title
Emergence of Atrial Fibrillation and Flutter in COVID-19 Patients: A Retrospective Cohort Study.
- Authors
Bhuiya, Tanzim; Shah, Paras P.; Lau, Wing Hang; Park, Timothy; Munshi, Rezwan F.; Hai, Ofek; Zeltser, Roman; Makaryus, Amgad N.
- Abstract
COVID-19 is associated with various cardiovascular complications, including arrhythmias. This study investigated the incidence of new-onset atrial fibrillation (AFB) and atrial flutter (AFL) in COVID-19 patients and identified potential risk factors. We conducted a retrospective cohort study at a tertiary-care safety-net community hospital including 647 patients diagnosed with COVID-19 from March 2020 to March 2021. Patients with a prior history of AFB or AFL were excluded. Data on demographics, clinical characteristics, and outcomes were collected and analyzed using chi-square tests, t-tests, and binary logistic regression. We found that 69 patients (10.66%) developed AFB or AFL, with 41 patients (6.34%) experiencing new-onset arrhythmias. The incidence rates for new-onset AFB and AFL were 5.4% and 0.9%, respectively. Older age (≥65 years) was significantly associated with new-onset AFB/AFL (OR: 5.43; 95% CI: 2.31–12.77; p < 0.001), as was the development of sepsis (OR: 2.73; 95% CI: 1.31–5.70; p = 0.008). No significant association was found with patient sex. Our findings indicate that new-onset atrial arrhythmias are a significant complication in COVID-19 patients, particularly among the elderly and those with sepsis. This highlights the need for targeted monitoring and management strategies to mitigate the burden of atrial arrhythmias in high-risk populations during COVID-19 infection.
- Subjects
ATRIAL fibrillation risk factors; RISK assessment; T-test (Statistics); LOGISTIC regression analysis; RETROSPECTIVE studies; TERTIARY care; CHI-squared test; DESCRIPTIVE statistics; LONGITUDINAL method; ODDS ratio; SEPSIS; ATRIAL arrhythmias; MEDICAL records; ACQUISITION of data; ATRIAL flutter; CONFIDENCE intervals; COVID-19; DISEASE risk factors
- Publication
Healthcare (2227-9032), 2024, Vol 12, Issue 17, p1682
- ISSN
2227-9032
- Publication type
Article
- DOI
10.3390/healthcare12171682